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DKK1 抗体 (AA 32-266)

This anti-DKK1 antibody is a 兔多克隆 antibody detecting DKK1 in WB. Suitable for 人, 大鼠和小鼠.

产品编号 ABIN6719383

发货至: 中国

Quick Overview for DKK1 抗体 (AA 32-266) (ABIN6719383)

抗原

See all DKK1 抗体

DKK1 (Dickkopf Homolog 1 (DKK1))

适用

128
41
35
18
4
4
4
3
3
3
3
3
2
1
1
1
1
1

人, 大鼠, 小鼠

宿主

兔

克隆类型

多克隆

标记

91
13
9
5
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1

This DKK1 antibody is un-conjugated

应用范围

101
54
49
29
28
13
13
13
8
4
4
3
1
1
1
1
1
1

Western Blotting (WB)

Discover our top product DKK1 Primary Antibody

抗原表位
16

15

10

8

6

6

5

5

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 32-266

原理

Anti-DKK1 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-DKK1 Antibody Picoband® (ABIN6719383). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived human DKK1 recombinant protein (Position: T32-H266).

亚型

IgG
anti-Dickkopf Homolog 1 (DKK1) (AA 1-266) antibody
DKK1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB52126 unconjugated

anti-Dickkopf Homolog 1 (DKK1) (AA 1-266) antibody
DKK1 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2A5 unconjugated

anti-Dickkopf Homolog 1 (DKK1) (AA 33-266) antibody
DKK1 适用: 人 WB 宿主: 小鼠 Monoclonal C5 unconjugated

anti-Dickkopf Homolog 1 (DKK1) (AA 81-180) antibody
DKK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C10 unconjugated

anti-Dickkopf Homolog 1 (DKK1) (AA 201-266) antibody
DKK1 适用: 人, 犬 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 1 (DKK1) (AA 36-260) antibody
DKK1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 1 (DKK1) (AA 33-266) antibody
DKK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 1 (DKK1) (AA 33-266) antibody
DKK1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 1 (DKK1) (Internal Region) antibody
DKK1 适用: 人, 马, Pig, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Dickkopf Homolog 1 (DKK1) (C-Term) antibody
Verified DKK1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
1. Fedi, P., Bafico, A., Soria, A. N., Burgess, W. H., Miki, T., Bottaro, D. P., Kraus, M. H., Aaronson, S. A.Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling.J. Biol. Chem. 274: 19465-19472, 1999. 2. Roessler, E., Du, Y., Glinka, A., Dutra, A., Niehrs, C., Muenke, M.The genomic structure, chromosome location, and analysis of the human DKK1 head inducer gene as a candidate for holoprosencephaly. Cytogenet. Cell Genet. 89: 220-224, 2000. 3. Tian, E., Zhan, F., Walker, R., Rasmussen, E., Ma, Y., Barlogie, B., Shaughnessy, J. D., Jr.The role of Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma.New Eng. J. Med. 349: 2483-2494, 2003.

说明

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

DKK1 (Dickkopf Homolog 1 (DKK1))

别名

DKK1

背景

Synonyms: Dickkopf-related protein 1, Dickkopf-1, Dkk-1, hDkk-1, SK, DKK1, UNQ492/PRO1008
Tissue Specificity: Placenta.
Background: DKK1, Dickkopf-related protein 1, is a protein that in humans is encoded by the DKK1 gene. This gene encodes a protein that is a member of the dickkopf family. By genomic sequence analysis, determined that the DKK1 gene contains 4 exons. The DKK1 gene is mapped to 10q11.2 using FISH. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

分子量

38 kDa

基因ID

22943

UniProt

O94907

途径

WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation

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