LUM 抗体 (AA 50-338)
Quick Overview for LUM 抗体 (AA 50-338) (ABIN6719339)
抗原
See all LUM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-338
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原理
- Anti-Lumican Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Lumican Antibody Picoband® (ABIN6719339). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Lumican recombinant protein (Position: A50-N338).
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亚型
- IgG
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anti-Lumican (LUM) (AA 19-338) antibody
LUM 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lumican (LUM) antibodyLUM 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Lumican (LUM) (AA 64-91), (N-Term) antibodyLUM 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18422 unconjugated
anti-Lumican (LUM) (AA 61-160) antibodyLUM 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lumican (LUM) (AA 19-338) antibodyLUM 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lumican (LUM) (AA 1-338) antibodyLUM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lumican (LUM) (N-Term) antibodyLUM 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lumican (LUM) (AA 19-338) antibodyLUM 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lumican (LUM) (AA 198-227) antibodyLUM 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18423 unconjugated
anti-Lumican (LUM) antibodyLUM 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: LUM lumican". 2. Chakravarti S, Stallings RL, SundarRaj N, Cornuet PK, Hassell JR (Jun 1995). "Primary structure of human lumican (keratan sulfate proteoglycan) and localization of the gene (LUM) to chromosome 12q21.3-q22". Genomics27 (3): 481-8. 3. Chakravarti S (2002). "Functions of lumican and fibromodulin: lessons from knockout mice". Glycoconjugate Journal 19 (4-5): 287-93. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- LUM (Lumican (LUM))
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别名
- LUM
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背景
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Synonyms: Lumican, Keratan sulfate proteoglycan lumican, KSPG lumican, LUM, LDC, SLRR2D,
Tissue Specificity: Cornea and other tissues.
Background: Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12. Lumican is a major keratan sulfate proteoglycan of the cornea but is ubiquitously distributed in most mesenchymal tissues throughout the body. And Lumican is involved in collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. Corneal transparency is possible due to the exact alignment of collagen fibers by lumican (and keratocan) in the intrafibrillar space.
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分子量
- 58 kDa
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基因ID
- 4060
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UniProt
- P51884
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途径
- Glycosaminoglycan Metabolic Process
抗原
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