EWSR1 抗体 (Middle Region)
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- 抗原 See all EWSR1 抗体
- EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))
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抗原表位
- AA 369-399, Middle Region
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适用
- 人, 小鼠, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This EWSR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Mouse IgG monoclonal antibody for EWSR1 detection. Tested with WB, IHC-P in Human,Mouse,Monkey.
- 序列
- NDSVTLDDLA DFFKQCGVVK MNKRTGQPMI H
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Mouse IgG monoclonal antibody for EWSR1 detection. Tested with WB, IHC-P in Human,Mouse,Monkey.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human EWSR1 (369-399aa NDSVTLDDLADFFKQCGVVKMNKRTGQPMIH), different from the related mouse sequence by one amino acid.
- 克隆位点
- 4B4
- 亚型
- IgG
- Top Product
- Discover our top product EWSR1 Primary Antibody
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anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) (Internal Region) antibody
Verified EWSR1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) antibodyEWSR1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) (AA 358-453) antibodyEWSR1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5C10 unconjugated
anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) (Middle Region) antibodyEWSR1 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) antibodyEWSR1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) (Internal Region) antibodyEWSR1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) (AA 358-453) antibodyEWSR1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) (AA 369-399), (Middle Region) antibodyEWSR1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) (N-Term) antibodyEWSR1 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 豚鼠, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ewing Sarcoma Breakpoint Region 1 (EWSR1) (AA 1-300) antibodyEWSR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL
- 说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))
- 别名
- EWSR1 (EWSR1 产品)
- 别名
- EWS antibody, bK984G1.4 antibody, AU018891 antibody, Ews antibody, Ewsh antibody, EWSR1 antibody, fc04c01 antibody, wu:fc04c01 antibody, DKFZp459K1116 antibody, ewsr1 antibody, ewsr1.S antibody, fb40b11 antibody, fusl antibody, wu:fb40b11 antibody, wu:fb75g09 antibody, zgc:55864 antibody, EWS RNA binding protein 1 antibody, Ewing sarcoma breakpoint region 1 antibody, EWS RNA-binding protein 1 antibody, EWS RNA-binding protein 1a antibody, EWS RNA binding protein 1 L homeolog antibody, EWS RNA-binding protein 1b antibody, EWSR1 antibody, Ewsr1 antibody, ewsr1a antibody, ewsr1 antibody, ewsr1.L antibody, ewsr1b antibody
- 背景
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Synonyms: RNA-binding protein EWS, EWS oncogene, Ewing sarcoma breakpoint region 1 protein, EWSR1, EWS
Background: This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11,22)(q24,q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
- 基因ID
- 2130
- UniProt
- Q01844
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