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CNR1 抗体 (AA 1-75) (DyLight 550)

This anti-CNR1 antibody is a 兔 多克隆 antibody detecting CNR1 in FACS. Suitable for 人.
产品编号 ABIN7354602
发货至: 中国

Quick Overview for CNR1 抗体 (AA 1-75) (DyLight 550) (ABIN7354602)

抗原

See all CNR1 抗体
CNR1 (Cannabinoid Receptor 1 (CNR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This CNR1 antibody is conjugated to DyLight 550

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-75

    原理

    Anti-Human Cannabinoid Receptor I DyLight® 550 conjugated CNR1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Human Cannabinoid Receptor I DyLight® 550 conjugated CNR1 Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Cannabinoid Receptor I recombinant protein (Position: M1-Q75).

    亚型

    IgG
  • 应用备注

    Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. "Entrez Gene: CNR1 cannabinoid receptor 1 (brain)". 2. Russo, P., Strazzullo, P., Cappuccio, F. P., Tregouet, D. A., Lauria, F., Loguercio, M., Barba, G., Versiero, M., Siani, A. Genetic variations at the endocannabinoid type 1 receptor gene (CNR1) are associated with obesity phenotypes in men. J. Clin. Endocr. Metab. 92: 2382-2386, 2007.

    说明

    Other applications have not been tested. Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
  • 抗原

    CNR1 (Cannabinoid Receptor 1 (CNR1))

    别名

    CNR1

    背景

    Synonyms: Cannabinoid receptor 1, CB-R, CB1, CANN6, CNR1, CNR

    Tissue Specificity: Widely expressed, with highest levels in fetal and adult brain. Expression levels of isoform 2 and isoform 3 are much lower than those of isoform 1.

    Background: The cannabinoid receptor type 1, often abbreviated as CB1, is a G protein-coupled cannabinoid receptor located primarily in the central and peripheral nervous system. This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

    分子量

    39 kDa

    基因ID

    1268

    UniProt

    P21554

    途径

    Feeding Behaviour
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