PLG 抗体
Quick Overview for PLG 抗体 (ABIN6719276)
抗原
See all PLG 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-Plasminogen/PLG Antibody Picoband®
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序列
- EPLDDYVNTQ GASLFSVTKK QL
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Plasminogen/PLG Antibody Picoband® (ABIN6719276). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Plasminogen, which shares 72.7% amino acid (aa) sequence identity with both mouse and rat Plasminogen.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Forsgren, M., Raden, B., Israelsson, M., Larsson, K., Heden, L.-O. Molecular cloning and characterization of a full-length cDNA clone for human plasminogen. FEBS Lett. 213: 254-260, 1987. 2. Miyata, T., Iwanaga, S., Sakata, Y., Aoki, N. Plasminogen Tochigi: inactive plasmin resulting from replacement of alanine-600 by threonine in the active site. Proc. Nat. Acad. Sci. 79: 6132-6136, 1982. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PLG (Plasminogen (PLG))
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别名
- PLG
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背景
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Synonyms: Plasminogen, Plasmin heavy chain A, Activation peptide, Angiostatin, Plasmin heavy chain A, short form, Plasmin light chain B, PLG
Tissue Specificity: Present in plasma and many other extracellular fluids. It is synthesized in the liver.
Background: Plasminogen (PLG) is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase (PLAU) and tissue plasminogen activator (PLAT). The main function of plasmin is to dissolve fibrin (see, e.g., FGA) clots. Plasmin, like trypsin, belongs to the family of serine proteinases. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis.
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分子量
- 100 kDa
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基因ID
- 5340
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UniProt
- P00747
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途径
- Complement System, Lipid Metabolism
抗原
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