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Amphiregulin 抗体 (AA 100-191)

This 兔 多克隆 antibody specifically detects Amphiregulin in WB, IHC, ELISA 和 FACS. It exhibits reactivity toward 小鼠 和 大鼠.
产品编号 ABIN6719275
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Amphiregulin 抗体 (AA 100-191) (ABIN6719275)

抗原

See all Amphiregulin (AREG) 抗体
Amphiregulin (AREG)

适用

  • 51
  • 22
  • 15
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 55
  • 12
  • 1
  • 1

克隆类型

  • 55
  • 11
  • 2
多克隆

标记

  • 35
  • 6
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  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Amphiregulin antibody is un-conjugated

应用范围

  • 35
  • 23
  • 20
  • 19
  • 7
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 13
    • 11
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-191

    原理

    Anti-Amphiregulin/Areg Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Amphiregulin/Areg Antibody. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived mouse Amphiregulin recombinant protein (Position:V100-K191).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Rat ELISA (Cap), 1-5 μg/mL, -

    说明

    Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Amphiregulin (AREG)

    别名

    Areg

    背景

    Background: Amphiregulin, also known as AREG, is a protein that in humans is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells. It is mapped to 9q32. It has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage.

    Gene Full Name: amphiregulin

    分子量

    45 kDa

    基因ID

    11839

    UniProt

    P31955

    途径

    RTK signaling, EGFR Signaling Pathway
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