Amphiregulin 抗体 (AA 100-191)
Quick Overview for Amphiregulin 抗体 (AA 100-191) (ABIN6719275)
抗原
See all Amphiregulin (AREG) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 100-191
-
原理
- Anti-Amphiregulin/Areg Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Amphiregulin/Areg Antibody Picoband® (ABIN6719275). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived mouse Amphiregulin recombinant protein (Position:V100-K191).
-
亚型
- IgG
-
-
anti-Amphiregulin (AREG) (AA 185-252) antibody
AREG 适用: 人, 小鼠, 大鼠, 豚鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 20-100) antibodyAREG 适用: 人 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal A3 unconjugated
anti-Amphiregulin (AREG) (AA 20-252) antibodyAREG 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 20-129) antibodyAREG 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3E4 unconjugated
anti-Amphiregulin (AREG) (AA 107-148) antibodyAREG 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 20-100) antibodyAREG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 97-243) antibodyAREG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 94-191) antibodyAREG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 27-247) antibodyAREG 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Amphiregulin (AREG) (AA 1-252) antibodyAREG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA (Cap), 1-5 μg/mL
1. Ciarloni, L., Mallepell, S., Brisken, C. Amphiregulin is an essential mediator of estrogen receptor alpha function in mammary gland development. Proc. Nat. Acad. Sci. 104: 5455-5460, 2007. 2. Cook, P. W., Piepkorn, M., Clegg, C. H., Plowman, G. D., DeMay, J. M., Brown, J. R., Pittelkow, M. R. Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype. J. Clin. Invest. 100: 2286-2294, 1997. -
说明
-
Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- Amphiregulin (AREG)
-
别名
- Areg
-
背景
-
Synonyms: Amphiregulin, AR, Schwannoma-derived growth factor, SDGF, Areg, Sdgf
Tissue Specificity: Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.
Background: Amphiregulin, also known as AREG, is a protein that in humans is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells. It is mapped to 9q32. It has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage.
-
分子量
- 41 kDa
-
基因ID
- 11839
-
UniProt
- P31955
-
途径
- RTK signaling, EGFR Signaling Pathway
抗原
-
