DMBT1 抗体 (AA 1701-1785)
Our Local Distributor
北京 101111
Quick Overview for DMBT1 抗体 (AA 1701-1785) (ABIN670626)
抗原
See all DMBT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1701-1785
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human GP340
-
亚型
- IgG
-
-
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) antibody
DMBT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 2008-2413) antibodyDMBT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) antibodyDMBT1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 2160-2192) antibodyDMBT1 适用: 大鼠 WB 宿主: 兔 Polyclonal RB53896 unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) antibodyDMBT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
-
别名
- GP340
-
背景
-
Synonyms: GP340, muclin, Deleted in malignant brain tumors 1 protein, Glycoprotein 340, Gp-340, Hensin, Salivary agglutinin, SAG, Surfactant pulmonary-associated D-binding protein, DMBT1, DMBT1/6kb.1
Background: May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH -dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell.
-
基因ID
- 1755
-
UniProt
- Q9UGM3
-
途径
- Activation of Innate immune Response
抗原
-
