DMBT1 抗体 (AA 1701-1785)
Quick Overview for DMBT1 抗体 (AA 1701-1785) (ABIN670626)
抗原
See all DMBT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1701-1785
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交叉反应
- 小鼠
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预测反应
- Human,Rat
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GP340
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亚型
- IgG
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anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) antibody
DMBT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 2008-2413) antibodyDMBT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) antibodyDMBT1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (AA 2160-2192) antibodyDMBT1 适用: 大鼠 WB 宿主: 兔 Polyclonal RB53896 unconjugated
anti-Deleted in Malignant Brain Tumors 1 (DMBT1) (N-Term) antibodyDMBT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))
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别名
- GP340
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背景
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Synonyms: GP340, muclin, Deleted in malignant brain tumors 1 protein, Glycoprotein 340, Gp-340, Hensin, Salivary agglutinin, SAG, Surfactant pulmonary-associated D-binding protein, DMBT1, DMBT1/6kb.1
Background: May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH -dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell.
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基因ID
- 1755
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UniProt
- Q9UGM3
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途径
- Activation of Innate immune Response
抗原
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