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Endoglin 抗体 (AA 601-658)

This anti-Endoglin antibody is a 兔 多克隆 antibody detecting Endoglin in ELISA 和 IHC (p). Suitable for 人 和 大鼠. This Primary Antibody has been cited in 8+ publications.
产品编号 ABIN670401
发货至: 中国

Quick Overview for Endoglin 抗体 (AA 601-658) (ABIN670401)

抗原

See all Endoglin (ENG) 抗体
Endoglin (ENG)

适用

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人, 大鼠

宿主

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  • 16
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  • 2
  • 1

克隆类型

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多克隆

标记

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This Endoglin antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 15
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    • 11
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    • 7
    • 4
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    • 1
    • 1
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    • 1
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    • 1
    • 1
    AA 601-658

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CD105

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Hussien, Ebrahim, Mohammed, Sabry: "Combination of Obestatin and Bone Marrow Mesenchymal Stem Cells Prevents Aggravation of Endocrine Pancreatic Damage in Type II Diabetic Rats." in: International journal of stem cells, Vol. 10, Issue 2, pp. 129-143, (2017) (PubMed).

    Li, Cai, Yang, Zhang, Sun, Yan, Qu, Wang, Wang, Duan: "Perichondrium mesenchymal stem cells inhibit the growth of breast cancer cells via the DKK-1/Wnt/β-catenin signaling pathway." in: Oncology reports, Vol. 36, Issue 2, pp. 936-44, (2017) (PubMed).

    Naderi-Meshkin, Matin, Heirani-Tabasi, Mirahmadi, Irfan-Maqsood, Edalatmanesh, Shahriyari, Ahmadiankia, Moussavi, Bidkhori, Bahrami: "Injectable hydrogel delivery plus preconditioning of mesenchymal stem cells: exploitation of SDF-1/CXCR4 axis towards enhancing the efficacy of stem cells' homing." in: Cell biology international, (2015) (PubMed).

    Fan, Chen, Ni, Wang, Sun, Chen, Zheng: "Expression of MMP-1/PAR-1 and patterns of invasion in oral squamous cell carcinoma as potential prognostic markers." in: OncoTargets and therapy, Vol. 8, pp. 1619-26, (2015) (PubMed).

    Tepekoy, Ozturk, Sozen, Ozay, Akkoyunlu, Demir: "CD90 and CD105 expression in the mouse ovary and testis at different stages of postnatal development." in: Reproductive biology, Vol. 15, Issue 4, pp. 195-204, (2015) (PubMed).

    Boopathy, Pendergrass, Che, Yoon, Davis: "Oxidative stress-induced Notch1 signaling promotes cardiogenic gene expression in mesenchymal stem cells." in: Stem cell research & therapy, Vol. 4, Issue 2, pp. 43, (2014) (PubMed).

    Gao, Zhang, Ding, Chen, Hu, Jiang, Li, Chen, Wang, Ye, Zhu: "Common expression of stemness molecular markers and early cardiac transcription factors in human Wharton's jelly-derived mesenchymal stem cells and embryonic stem cells." in: Cell transplantation, Vol. 22, Issue 10, pp. 1883-900, (2014) (PubMed).

  • 抗原

    Endoglin (ENG)

    别名

    CD105

    背景

    Synonyms: END, HHT1, ORW1, Endoglin, CD15, ENG

    Background: Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

    基因ID

    2022

    UniProt

    P17813
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