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ATF3 抗体 (AA 51-150)

This anti-ATF3 antibody is a 兔 多克隆 antibody detecting ATF3 in WB, FACS, IF (p) 和 IHC (p). Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN669561
发货至: 中国

Quick Overview for ATF3 抗体 (AA 51-150) (ABIN669561)

抗原

See all ATF3 抗体
ATF3 (Activating Transcription Factor 3 (ATF3))

适用

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人, 小鼠, 大鼠

宿主

  • 61
  • 12

克隆类型

  • 60
  • 13
多克隆

标记

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This ATF3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
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    • 11
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    • 1
    • 1
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    • 1
    • 1
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    AA 51-150

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ATF3

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Smith, Seto, Vivekanandan-Giri, Yuan, Playford, Manna, Hasni, Kuai, Mehta, Schwendeman, Pennathur, Kaplan et al.: "Lupus high-density lipoprotein induces proinflammatory responses in macrophages by binding lectin-like oxidised low-density lipoprotein receptor 1 and failing to promote activating transcription ..." in: Annals of the rheumatic diseases, (2016) (PubMed).

    Aguirre, López-Alonso, González-López, Amado-Rodríguez, Batalla-Solís, Astudillo, Blázquez-Prieto, Fernández, Galván, dos Santos, Albaiceta: "Defective autophagy impairs ATF3 activity and worsens lung injury during endotoxemia." in: Journal of molecular medicine (Berlin, Germany), Vol. 92, Issue 6, pp. 665-76, (2014) (PubMed).

    Yuan, Han, Cong, Ge, Ma, Dai, Li, Bi: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).

    Hu, Li, Li: "MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1." in: PLoS ONE, Vol. 8, Issue 6, pp. e68291, (2013) (PubMed).

    Feng, Sun, Wu, Lu, Qu, Sun, Tian, Zhang, Li, Liu: "Upregulation of ATF-3 is correlated with prognosis and proliferation of laryngeal cancer by regulating Cyclin D1 expression." in: International journal of clinical and experimental pathology, Vol. 6, Issue 10, pp. 2064-70, (2013) (PubMed).

  • 抗原

    ATF3 (Activating Transcription Factor 3 (ATF3))

    别名

    ATF3

    背景

    Synonyms: Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, ATF3

    Background: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.

    基因ID

    467

    UniProt

    P18847

    途径

    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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