SLC1A5 抗体 (AA 465-515)
Quick Overview for SLC1A5 抗体 (AA 465-515) (ABIN669081)
抗原
See all SLC1A5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 465-515
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SLC1A5
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亚型
- IgG
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应用备注
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ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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Cytotoxic stress induces transfer of mitochondria-associated human endogenous retroviral RNA and proteins between cancer cells." in: Oncotarget, Vol. 8, Issue 56, pp. 95945-95964, (2017) (PubMed).
: "Upregulated SLC1A5 promotes cell growth and survival in colorectal cancer." in: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 6006-14, (2014) (PubMed).
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Cytotoxic stress induces transfer of mitochondria-associated human endogenous retroviral RNA and proteins between cancer cells." in: Oncotarget, Vol. 8, Issue 56, pp. 95945-95964, (2017) (PubMed).
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- SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))
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别名
- SLC1A5
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背景
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Synonyms: R16, AAAT, ATBO, M7V1, RDRC, ASCT2, M7VS1, Neutral amino acid transporter B(0), ATB(0), Baboon M7 virus receptor, RD114/simian type D retrovirus receptor, Sodium-dependent neutral amino acid transporter type 2, Solute carrier family 1 member 5, SLC1A5, RDR
Background: Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).
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基因ID
- 6510
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UniProt
- Q15758
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途径
- Dicarboxylic Acid Transport, Warburg Effect
抗原
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