SLC1A5 抗体 (Middle Region)
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北京 101111
Quick Overview for SLC1A5 抗体 (Middle Region) (ABIN2775316)
抗原
See all SLC1A5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- SLC1A5 Antibody - middle region
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序列
- FGVALRKLGP EGELLIRFFN SFNEATMVLV SWIMWYAPVG IMFLVAGKIV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against SLC1A5. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SLC1A5
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42247-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Protein Restriction with Amino Acid-Balanced Diets Shrinks Circulating Pool Size of Amino Acid by Decreasing Expression of Specific Transporters in the Small Intestine." in: PLoS ONE, Vol. 11, Issue 9, pp. e0162475, (2016) (PubMed).
: "L-Glutamine deprivation induces autophagy and alters the mTOR and MAPK signaling pathways in porcine intestinal epithelial cells." in: Amino acids, Vol. 47, Issue 10, pp. 2185-97, (2015) (PubMed).
: "Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers." in: Archives of biochemistry and biophysics, Vol. 443, Issue 1-2, pp. 53-9, (2005) (PubMed).
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- SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))
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别名
- SLC1A5
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背景
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Background Information: SLC1A5 has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. It acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses.
Gene Name: Solute carrier family 1 (neutral amino acid transporter), member 5
Alternative Symbols: R16, AAAT, ATBO, M7V1, RDRC, ASCT2, M7VS1
Protein Name: Neutral amino acid transporter EMBL AAD09814.1
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分子量
- 57 kDa
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基因ID
- 6510
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NCBI登录号
- NP_005619
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UniProt
- Q71UA6
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途径
- Dicarboxylic Acid Transport, Warburg Effect
抗原
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