Ghrelin 抗体 (AA 31-117)
Quick Overview for Ghrelin 抗体 (AA 31-117) (ABIN668991)
抗原
See all Ghrelin (GHRL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-117
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Ghrelin
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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Ghrelin protects the myocardium with hypoxia/reoxygenation treatment through upregulating the expression of growth hormone, growth hormone secretagogue receptor and insulin-like growth factor-1, and ..." in: International journal of molecular medicine, Vol. 42, Issue 6, pp. 3037-3046, (2019) (PubMed).
: "Deregulation of transcription factors controlling intestinal epithelial cell differentiation; a predisposing factor for reduced enteroendocrine cell number in morbidly obese individuals." in: Scientific reports, Vol. 7, Issue 1, pp. 8174, (2017) (PubMed).
: "Effects of zearalenone-diet on expression of ghrelin and PCNA genes in ovaries of post-weaning piglets." in: Animal reproduction science, Vol. 168, pp. 126-37, (2016) (PubMed).
: "Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat." in: PLoS ONE, Vol. 10, Issue 7, pp. e0133600, (2015) (PubMed).
: "Effects of Wen Dan Tang on insomnia-related anxiety and levels of the brain-gut peptide Ghrelin." in: Neural regeneration research, Vol. 9, Issue 2, pp. 205-12, (2014) (PubMed).
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Ghrelin protects the myocardium with hypoxia/reoxygenation treatment through upregulating the expression of growth hormone, growth hormone secretagogue receptor and insulin-like growth factor-1, and ..." in: International journal of molecular medicine, Vol. 42, Issue 6, pp. 3037-3046, (2019) (PubMed).
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- Ghrelin (GHRL)
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别名
- Ghrelin
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背景
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Synonyms: MTLRP, Appetite-regulating hormone, Growth hormone secretagogue, Growth hormone-releasing peptide, Motilin-related peptide, Protein M46, GHRL, UNQ524/PRO1066
Background: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
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基因ID
- 51738
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UniProt
- Q9UBU3
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途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour
抗原
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