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WNK4 抗体 (Cy5)

WNK4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal Cy5
产品编号 ABIN668530
发货至: 中国
  • 抗原 See all WNK4 抗体
    WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))
    适用
    • 45
    • 29
    • 25
    • 4
    • 1
    人, 小鼠, 大鼠
    宿主
    • 46
    • 2
    克隆类型
    • 46
    • 2
    多克隆
    标记
    • 13
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WNK4 antibody is conjugated to Cy5
    应用范围
    • 28
    • 25
    • 8
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠
    预测反应
    Human,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human WNK4
    亚型
    IgG
    Top Product
    Discover our top product WNK4 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    WNK4 (WNK Lysine Deficient Protein Kinase 4 (WNK4))
    别名
    WNK4 (WNK4 产品)
    别名
    WNK4 antibody, PHA2B antibody, PRKWNK4 antibody, 2010002J11Rik antibody, Pha2b antibody, Prkwnk4 antibody, Ac2-059 antibody, WNK lysine deficient protein kinase 4 antibody, WNK4 antibody, Wnk4 antibody
    背景

    Synonyms: PHA 2B, PHA2B, PRKWNK 4, PRKWNK4, Protein kinase lysine deficient 4, Protein kinase with no lysine 4, Serine/threonine protein kinase WNK4, WNK lysine deficient protein kinase 4, WNK4_HUMAN.

    Background: Regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation which appears to prevent membrane trafficking of SLC12A3. Also inhibits the renal K(+)channel, KCNJ1, via a kinase-independent mechanism by which it induces clearance of the protein from the cell surface by clathrin-dependent endocytosis. WNK4 appears to act as a molecular switch that can vary the balance between NaCl reabsorption and K(+)secretion to maintain integrated homeostasis.

    基因ID
    65266
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