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TIMP2 抗体 (AA 131-220)

This anti-TIMP2 antibody is a 兔 多克隆 antibody detecting TIMP2 in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人 和 大鼠. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN668346
发货至: 中国

Quick Overview for TIMP2 抗体 (AA 131-220) (ABIN668346)

抗原

See all TIMP2 抗体
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TIMP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 131-220

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Sheep,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TIMP-2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Varghese, Joseph, S R, B S, Sreelekha: "The inhibitory effect of anti- tumor polysaccharide from Punica granatum on metastasis." in: International journal of biological macromolecules, Vol. 103, pp. 1000-1010, (2017) (PubMed).

    Lu, Huang, Shih, Chang, Tsai, Lin, Shih: "Dipeptidyl peptidase-4 inhibitor decreases abdominal aortic aneurysm formation through GLP-1-dependent monocytic activity in mice." in: PLoS ONE, Vol. 10, Issue 4, pp. e0121077, (2015) (PubMed).

    Ni, Ding, Zhou, Qiu, Tang: "Renoprotective effects of berberine through regulation of the MMPs/TIMPs system in streptozocin-induced diabetic nephropathy in rats." in: European journal of pharmacology, Vol. 764, pp. 448-456, (2015) (PubMed).

    Watts, Bilska, Diab, Dunster, Bulmer, Barnett, Fraser: "Novel 24-h ovine model of brain death to study the profile of the endothelin axis during cardiopulmonary injury." in: Intensive care medicine experimental, Vol. 3, Issue 1, pp. 31, (2015) (PubMed).

    Fang, Wu, Huang: "Raloxifene upregulated mesangial cell MMP-2 activity via ER-? through transcriptional regulation." in: Cell biochemistry and biophysics, Vol. 67, Issue 2, pp. 607-13, (2013) (PubMed).

    He, Li, Su, Shen, Liu, Ma, Zhao, Zhang: "Single minded 2-s (SIM2-s) gene is expressed in human GBM cells and involved in GBM invasion." in: Cancer biology & therapy, Vol. 9, Issue 6, pp. 430-6, (2010) (PubMed).

  • 抗原

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    别名

    TIMP-2

    背景

    Synonyms: DDC8, CSC-21K, KIAA1731NL, Metalloproteinase inhibitor 2, Tissue inhibitor of metalloproteinases 2, TIMP-2, TIMP2

    Background: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-1, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.

    基因ID

    7077

    UniProt

    P16035

    途径

    cAMP Metabolic Process
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