MMP2 抗体 (AA 31-109) (Biotin)
Quick Overview for MMP2 抗体 (AA 31-109) (Biotin) (ABIN668288)
抗原
See all MMP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 31-109
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交叉反应
- 人, 小鼠, 兔, 大鼠
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预测反应
- Cow,Sheep,Pig,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- MAT conjugated synthetic peptide derived from human MMP2
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亚型
- IgG
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anti-Matrix Metalloproteinase 2 (MMP2) (AA 31-109) antibody
MMP2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 40-280) antibodyMMP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) antibodyMMP2 适用: 人 WB, IP, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 401-500) antibodyMMP2 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibodyMMP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 9-140) antibodyMMP2 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2B11E6 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (C-Term) antibodyMMP2 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 马, 豚鼠, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 110-660) antibodyMMP2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 242-396) antibodyMMP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D1E2 unconjugated
anti-Matrix Metalloproteinase 2 (MMP2) (AA 9-140) antibodyMMP2 适用: 人, 小鼠 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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别名
- MMP2
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背景
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Synonyms: CLG4, MONA, CLG4A, MMP-2, TBE-1, MMP-II, 72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP2
Background: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
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基因ID
- 4313
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UniProt
- P08253
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途径
- Activation of Innate immune Response
抗原
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