NMDAR2A 抗体 (N-Term)
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- 抗原 See all NMDAR2A (GRIN2A) 抗体
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
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抗原表位
- N-Term
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NMDAR2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Anti-NMDA R2A antibody is directed against NMDA R2A protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Expect reactivity with the following species based on 100% sequence homology: bovine, canine and mouse.
- 免疫原
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Immunogen: Anti-NMDA R2A Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the N-terminal region of the NR2A subunit.
Immunogen Type: Peptide
- 亚型
- IgG
- Top Product
- Discover our top product GRIN2A Primary Antibody
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anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 851-950) antibody
GRIN2A 适用: 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 501-750) antibodyGRIN2A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 1130-1400) antibodyGRIN2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) antibodyGRIN2A 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 23-165) antibodyGRIN2A 适用: 人 WB, IHC, ELISA, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 3G10F9 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibodyGRIN2A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S327-95 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibodyGRIN2A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S327A-38 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (HRP)GRIN2A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S327-95 HRP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (HRP)GRIN2A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S327A-38 HRP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (FITC)GRIN2A 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S327-95 FITC
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- 应用备注
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Immunohistochemistry Dilution: 1:500
Application Note: Anti-NMDA R2A Antibody is suitable for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 180 kDa in size corresponding to the NR2A subunit of the NMDA receptor in the appropriate cell lysate or extract.
Western Blot Dilution: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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: "Ablation of SNX6 leads to defects in synaptic function of CA1 pyramidal neurons and spatial memory." in: eLife, Vol. 6, (2018) (PubMed).
: "Post-acute delivery of memantine promotes post-ischemic neurological recovery, peri-infarct tissue remodeling, and contralesional brain plasticity." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 37, Issue 3, pp. 980-993, (2017) (PubMed).
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: "Ablation of SNX6 leads to defects in synaptic function of CA1 pyramidal neurons and spatial memory." in: eLife, Vol. 6, (2018) (PubMed).
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- 抗原
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
- 别名
- NMDA R2A (GRIN2A 产品)
- 别名
- NMDAR2A antibody, nr2a antibody, GRIN2A antibody, EPND antibody, GluN2A antibody, NR2A antibody, glutamate ionotropic receptor NMDA type subunit 2A antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog antibody, glutamate receptor ionotropic, NMDA 2A antibody, glutamate receptor, ionotropic, NMDA2A (epsilon 1) antibody, GRIN2A antibody, grin2a.L antibody, LOC100438553 antibody, Grin2a antibody
- 背景
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Synonyms: Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, Grin2a
Background: NMDA R2A Antibody detects NMDA R2A protein. The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death. The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS. The NMDAR is also potentiated by protein phosphorylation. The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Anti-NMDA R2A Antibody is ideal for investigators involved in Neuroscience, Cell Signaling, and Signal Transduction research.
Gene Name: GRIN2A
- 基因ID
- 24409
- UniProt
- Q00959
- 途径
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
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