GABBR2 抗体 (pSer783)
(1 reference)
Quick Overview for GABBR2 抗体 (pSer783) (ABIN6658229)
抗原
See all GABBR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer783
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Supplier Product No.
- 612-401-d53
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Supplier
- Rockland
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原理
- GABA(B) Receptor 2 phospho S783 Antibody
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交叉反应 （详细）
- Anti-GABA(B) Receptor 2 pS783 Antibody is directed against rat phosphorylated GABA(B) Receptor 2.
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纯化方法
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- Anti-GABA(B) Receptor 2 pS783 Antibody was produced by repeated immunizations with synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 783 of rat GABAB R2.
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亚型
- IgG
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anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody
GABBR2 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 5G7F7 unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 501-650) antibodyGABBR2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (pSer783) antibodyGABBR2 适用: 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibodyGABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (HRP)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 HRP
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (FITC)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 FITC
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (Biotin)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 Biotin
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (PE)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 PE
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (PerCP)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 PerCP
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (APC)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 APC
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应用备注
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IF_Microscopy_Dilution: 1:500
Western_Blot_Dilution: 1:1000
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说明
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Anti-GABA(B) Receptor 2 pS783 (Rabbit) antibody is tested for use in Western Blotting, ICC, and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 102 kDa in size corresponding to GABA(B) receptor 2 protein phosphorylated at Ser783 in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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: "Extracellular Signal-Regulated Kinases Mediate an Autoregulation of GABAB-Receptor-Activated Whole-Cell Current in Locus Coeruleus Neurons." in: Scientific reports, Vol. 10, Issue 1, pp. 7869, (2020) (PubMed).
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: "Extracellular Signal-Regulated Kinases Mediate an Autoregulation of GABAB-Receptor-Activated Whole-Cell Current in Locus Coeruleus Neurons." in: Scientific reports, Vol. 10, Issue 1, pp. 7869, (2020) (PubMed).
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- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
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别名
- GABA(B) Receptor 2
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背景
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Synonyms: Gamma-aminobutyric acid type B receptor subunit 2, GABA-B-R2, GABA-BR2, GABABR2, Gb2, G-protein coupled receptor 51
Background: Anti-GABA(A) Receptor 2 pS783 Antibody detects phosphorylated GABA(A) Receptor 2. Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. It has recently been demonstrated that AMPK binds directly to GABAB receptors and phosphorylates S783 in the cytoplasmic tail of the R2 subunit and that S783 plays a critical role in enhancing neuronal survival after ischemia as phosphorylation of S783 is evident in many brain regions and is increased dramatically after ischemic injury to the brain. GABA(B) Receptor 2 pS783 antibody is ideal for investigators involved in Neuroscience.
Gene Name: GABBR2
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基因ID
- 83633, 8393403
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UniProt
- O88871
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途径
- cAMP Metabolic Process
抗原
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