GABBR2 抗体 (AA 501-650)
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- 抗原 See all GABBR2 抗体
- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
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抗原表位
- AA 501-650
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GABBR2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GABA B Receptor 2
- 亚型
- IgG
- Top Product
- Discover our top product GABBR2 Primary Antibody
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anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody
GABBR2 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 5G7F7 unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibodyGABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 unconjugated
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (HRP)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 HRP
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (FITC)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 FITC
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (Biotin)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 Biotin
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (PE)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 PE
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (APC)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 APC
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (PerCP)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 PerCP
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (Atto 488)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 Atto 488
anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 861-912) antibody (Atto 594)GABBR2 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S81-2 Atto 594
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- GABBR2 (gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
- 别名
- GABA B Receptor 2 (GABBR2 产品)
- 别名
- Gpr51 antibody, GABABR2 antibody, GPR51 antibody, GPRC3B antibody, HG20 antibody, HRIHFB2099 antibody, Gb2 antibody, Gm425 antibody, GABA(B)R2 antibody, si:dkey-190l1.2 antibody, gamma-aminobutyric acid type B receptor subunit 2 antibody, gamma-aminobutyric acid (GABA) B receptor, 2 antibody, gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog antibody, GABBR2 antibody, LOC100448699 antibody, gabbr2 antibody, Gabbr2 antibody, gabbr2.S antibody
- 背景
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Synonyms: HG20, GPR51, GPRC3B, GABABR2, HRIHFB2099, Gamma-aminobutyric acid type B receptor subunit 2, GABA-B receptor 2, GABA-B-R2, GABA-BR2, Gb2, G-protein coupled receptor 51, GABBR2
Background: Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
- 基因ID
- 9568
- UniProt
- O75899
- 途径
- cAMP Metabolic Process
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