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Glutamate Receptor 1 抗体 (pSer831)

Rockland 612-401-c82 GLUR1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
Rockland
产品编号 ABIN6658218
Supplier Product No.: 612-401-c82
发货至: 中国
  • 抗原 See all Glutamate Receptor 1 (GLUR1) 抗体
    Glutamate Receptor 1 (GLUR1)
    抗原表位
    • 18
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    pSer831
    适用
    • 110
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    • 1
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    大鼠
    宿主
    • 121
    • 29
    • 1
    克隆类型
    • 112
    • 39
    多克隆
    标记
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    This Glutamate Receptor 1 antibody is un-conjugated
    应用范围
    • 104
    • 40
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    • 37
    • 27
    • 15
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    • 12
    • 5
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    Western Blotting (WB)
    Supplier Product No.
    612-401-c82
    Supplier
    Rockland
    原理
    GluR1 phospho S831 Antibody
    交叉反应 (详细)
    Anti-GluR1 pS831 Antibody is directed against rat GluR1.
    纯化方法
    The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
    免疫原
    Anti-GluR1 pS831 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 831.
    亚型
    IgG
    Top Product
    Discover our top product GLUR1 Primary Antibody
  • 应用备注
    Optional[Neutralization_Dilution]: 1:1000
    说明

    Anti-GluR1 pS831 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 100 kDa in size corresponding to the GluR1 protein phosphorylated at Ser 831 in the appropriate cell lysate or extract.

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

    Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    Glutamate Receptor 1 (GLUR1)
    别名
    GluR1 (GLUR1 产品)
    背景

    Synonyms: Glutamate receptor 1, GluR1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1,

    Background: GluR1 pS831 Antibody detects GluR1. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR1 subunit is widely expressed throughout the nervous system. GluR1 is potentiated by phosphorylation at Ser 831 which has been shown to be mediated by either PKC or CaM kinase II. In addition, phosphorylation of this site has been linked to synaptic plasticity as well as learning and memory. Therefore, GluR1 pS831 antibody is ideal for investigators involved in Neuroscience.

    Gene Name: GRIA1

    基因ID
    50592
    NCBI登录号
    NP_113796
    UniProt
    P19490
    途径
    PI3K-Akt Signaling
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