Glutamate Receptor 1 抗体 (pSer831)
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- 抗原 See all Glutamate Receptor 1 (GLUR1) 抗体
- Glutamate Receptor 1 (GLUR1)
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抗原表位
- pSer831
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Glutamate Receptor 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- Supplier Product No.
- 612-401-c82
- Supplier
- Rockland
- 原理
- GluR1 phospho S831 Antibody
- 交叉反应 (详细)
- Anti-GluR1 pS831 Antibody is directed against rat GluR1.
- 纯化方法
- The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.
- 免疫原
- Anti-GluR1 pS831 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser 831.
- 亚型
- IgG
- Top Product
- Discover our top product GLUR1 Primary Antibody
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- 应用备注
- Optional[Neutralization_Dilution]: 1:1000
- 说明
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Anti-GluR1 pS831 (Rabbit) antibody is tested for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 100 kDa in size corresponding to the GluR1 protein phosphorylated at Ser 831 in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
- 有效期
- 12 months
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- 抗原
- Glutamate Receptor 1 (GLUR1)
- 别名
- GluR1 (GLUR1 产品)
- 背景
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Synonyms: Glutamate receptor 1, GluR1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1,
Background: GluR1 pS831 Antibody detects GluR1. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR1 subunit is widely expressed throughout the nervous system. GluR1 is potentiated by phosphorylation at Ser 831 which has been shown to be mediated by either PKC or CaM kinase II. In addition, phosphorylation of this site has been linked to synaptic plasticity as well as learning and memory. Therefore, GluR1 pS831 antibody is ideal for investigators involved in Neuroscience.
Gene Name: GRIA1
- 基因ID
- 50592
- NCBI登录号
- NP_113796
- UniProt
- P19490
- 途径
- PI3K-Akt Signaling
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