Glutamate Receptor 1 抗体 (N-Term)
Quick Overview for Glutamate Receptor 1 抗体 (N-Term) (ABIN6658217)
抗原
See all Glutamate Receptor 1 (GLUR1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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Supplier Product No.
- 200-301-d61
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Supplier
- Rockland
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原理
- GluR1 Antibody
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交叉反应 (详细)
- Anti-GluR1 Monoclonal Antibody is directed against rat GluR1 protein.
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纯化方法
- The antibody was Protein G purified from cell culture supernatant.
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免疫原
- Anti-GluR1 Monoclonal Antibody was produced by repeated immunizations with GluR1- Synthetic peptide corresponding to amino acid residues from the N-terminal region.
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亚型
- IgG2a
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应用备注
- Optional[Neutralization_Dilution]: 1:1000
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说明
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Suggested Applications: IF
Anti-GluR1 (Mouse) antibody has been tested by Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 100 kDa in size corresponding to GluR1 proteins in Western Blot in the appropriate cell lysate or extract. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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: "Properties of the epileptiform activity in the cingulate cortex of a mouse model of LIS1 dysfunction." in: Brain structure & function, Vol. 227, Issue 5, pp. 1599-1614, (2022) (PubMed).
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: "Properties of the epileptiform activity in the cingulate cortex of a mouse model of LIS1 dysfunction." in: Brain structure & function, Vol. 227, Issue 5, pp. 1599-1614, (2022) (PubMed).
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- Glutamate Receptor 1 (GLUR1)
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别名
- GluR1
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背景
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Synonyms: Glutamate receptor 1, GluR1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1,
Background: GluR1 Monoclonal Antibody detects GluR1. The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. GluR1 monoclonal antibody is ideal for investigators involved in Neuroscience.
Gene Name: GRIA1
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基因ID
- 50592
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UniProt
- P19490
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途径
- PI3K-Akt Signaling
抗原
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