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Ataxin 1 抗体 (AA 164-197) (HRP)

This HRP-conjugated 小鼠 单克隆 anti-Ataxin 1 antibody (Clone S76-8) specifically detects Ataxin 1 in WB, IHC, ELISA 和 IP. The antibody is reactive with 小鼠 samples.
Rockland
产品编号 ABIN6657678
Supplier Product No.: 200-303-w69
发货至: 中国
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Quick Overview for Ataxin 1 抗体 (AA 164-197) (HRP) (ABIN6657678)

抗原

See all Ataxin 1 (ATXN1) 抗体
Ataxin 1 (ATXN1)

适用

  • 98
  • 61
  • 36
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠

宿主

  • 73
  • 60
  • 1
小鼠

克隆类型

  • 71
  • 63
单克隆

标记

  • 49
  • 9
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This Ataxin 1 antibody is conjugated to HRP

应用范围

  • 96
  • 50
  • 47
  • 46
  • 35
  • 32
  • 23
  • 23
  • 9
  • 8
  • 6
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

克隆位点

S76-8
  • 抗原表位

    • 28
    • 28
    • 22
    • 12
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 164-197

    Supplier Product No.

    200-303-w69

    Supplier

    Rockland

    原理

    Ataxin 1 Antibody Peroxidase

    交叉反应 (详细)

    BLAST analysis suggests that it is 100 % identical to rat and 88 % identical to human.

    纯化方法

    Anti-Ataxin 1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

    过滤

    Sterile filtered

    免疫原

    Anti-Ataxin 1 Antibody was produced by repeated immunization of mice with a synthetic peptide containing amino acids 164-197 of mouse Ataxin 1.

    亚型

    IgG2b
  • 应用备注

    Immunoprecipitation_Dilution: User Optimized

    ELISA_Dilution: 1:10,000

    Immunohistochemistry_Dilution: User Optimized

    Western_Blot_Dilution: 1:1000

    Other: ICC/IF: 1:100

    说明

    Anti-Ataxin 1 HRP Conjugated Antibody is tested for Western Blots, Immunohistochemistry and Immunoprecipitation. Expect a band approximately ~85 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Preservative: 0.1 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    Ataxin 1 (ATXN1)

    别名

    Ataxin 1

    背景

    Synonyms: Ataxin-1, ATX1, Atxn1, D6S504E, OTTHUMP00000016065, SCA1, Spinocerebellar ataxia type 1 protein

    Background: Ataxin-1 is a member of the ATXN1 protein family and contains a single AXH domain. It is a neurodegenerative disorder protein thought to have a role in the metabolism of RNA as it has been shown to localize to the RNA and transcription dependent inclusions within the nucleus. A mutation of Ataxin-1 is the cause of spinocerebellar ataxia type-1 (SCA1), a progressive, neurodegenerative disease that is autosomal dominant and primarily affects the Purjinke cells found in brain stem neuronal populations and the cerebellum. Expression of Ataxin-1 is almost ubiquitous, except in the brain where it is isolated to populations of neurons.

    Gene Name: Ataxin 1

    基因ID

    20238

    UniProt

    P54254

    途径

    Synaptic Membrane
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