Ataxin 1 抗体 (AA 746-761)
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北京 101111
Quick Overview for Ataxin 1 抗体 (AA 746-761) (ABIN6657650)
抗原
See all Ataxin 1 (ATXN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 746-761
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Supplier Product No.
- 200-301-w87
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Supplier
- Rockland
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原理
- Ataxin 1 Antibody
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交叉反应 （详细）
- BLAST analysis suggests that it is 93 % identical to rat and 87 % identical to human.
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纯化方法
- Anti-Ataxin 1 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.
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过滤
- Sterile filtered
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免疫原
- Anti-Ataxin 1 Antibody was produced by repeated immunization of mice with a synthetic peptide containing amino acids 746-761 of mouse ataxin-1.
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亚型
- IgG1
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anti-Ataxin 1 (ATXN1) (AA 645-815) antibody
ATXN1 适用: 小鼠, 人, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4C7B11 unconjugated
anti-Ataxin 1 (ATXN1) antibodyATXN1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Ataxin 1 (ATXN1) (AA 645-815) antibodyATXN1 适用: 小鼠, 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2B8A2 unconjugated
anti-Ataxin 1 (ATXN1) (AA 569-807) antibodyATXN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (C-Term) antibodyATXN1 适用: 小鼠, 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 331-587) antibodyATXN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 746-761) antibodyATXN1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S65-37 unconjugated
anti-Ataxin 1 (ATXN1) (AA 164-197) antibodyATXN1 适用: 小鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S76-8 unconjugated
anti-Ataxin 1 (ATXN1) (AA 164-197) antibody (HRP)ATXN1 适用: 小鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S76-8 HRP
anti-Ataxin 1 (ATXN1) (AA 746-761) antibody (HRP)ATXN1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S65-37 HRP
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应用备注
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ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
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说明
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Anti-Ataxin 1 Antibody is suitable for Western Blots and Immunocytochemistry. Expect a band approximately ~85kDa on specific lysates or tissues. No cross reactivity against phosphor S751-Ataxin-1. Minimal cross reactivity against S751A mutant of Ataxin-1 by ELISA and immunofluorescence and negative by immunoblot. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: 0.1 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- Ataxin 1 (ATXN1)
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别名
- Ataxin 1
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背景
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Synonyms: Ataxin-1, ATX1, Atxn1, D6S504E, OTTHUMP00000016065, SCA1, Spinocerebellar ataxia type 1 protein, Spinocerebellar ataxia type 1 protein homolog
Background: Ataxin-1 is a member of the ATXN1 protein family and contains a single AXH domain. It is a neurodegenerative disorder protein thought to have a role in the metabolism of RNA as it has been shown to localize to the RNA and transcription dependent inclusions within the nucleus. A mutation of Ataxin-1 is the cause of spinocerebellar ataxia type-1 (SCA1), a progressive, neurodegenerative disease that is autosomal dominant and primarily affects the Purjinke cells found in brain stem neuronal populations and the cerebellum. Expression of Ataxin-1 is almost ubiquitous, except in the brain where it is isolated to populations of neurons. Anti-Ataxin-1 is ideal for research in Neuroscience.
Gene Name: Ataxin-1
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基因ID
- 20238
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UniProt
- P54254
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途径
- Synaptic Membrane
抗原
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