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MDC1 抗体 (N-Term)

The 小鼠 单克隆 anti-MDC1 antibody (Clone P2B11) (ABIN6657611) specifically detects MDC1 in FM. The antibody is reactive with 小鼠 samples.
Rockland
产品编号 ABIN6657611
Supplier Product No.: 200-301-g12
发货至: 中国
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Quick Overview for MDC1 抗体 (N-Term) (ABIN6657611)

抗原

See all MDC1 抗体
MDC1 (Mdc1 (MDC1))

适用

  • 58
  • 44
  • 16
  • 12
  • 11
  • 2
  • 1
  • 1
小鼠

宿主

  • 48
  • 27
小鼠

克隆类型

  • 48
  • 27
单克隆

标记

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  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This MDC1 antibody is un-conjugated

应用范围

  • 57
  • 22
  • 13
  • 13
  • 13
  • 13
  • 11
  • 10
  • 9
  • 6
  • 3
  • 2
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Fluorescence Microscopy (FM)

克隆位点

P2B11
  • 抗原表位

    • 20
    • 15
    • 10
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    N-Term

    Supplier Product No.

    200-301-g12

    Supplier

    Rockland

    原理

    Mdc1 Antibody

    交叉反应 (详细)

    A BLAST analysis was used to suggest cross-reactivity with MDC1 from Human, Mouse, Chimpanzee, and Bovine based on 100 % homology with the immunizing sequence.

    纯化方法

    Anti-MDC1 Antibody was purified by Protein G chromatography.

    过滤

    Sterile filtered

    免疫原

    MDC1 Antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to mouse MDC1 at and around the N-terminus region.

    亚型

    IgG1
  • 应用备注

    Optional[Neutralization_Dilution]: User Optimized

    说明

    Anti-MDC1 Antibody is suitable for use in WB and IF microscopy. Expect a band approximately ~184kDa corresponding to specific lysates. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    MDC1 (Mdc1 (MDC1))

    别名

    MDC1

    背景

    Synonyms: Nuclear factor with BRCT domains1, mediator of DNA damage checkpoint 1, Kiaa0170

    Background: MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.

    Gene Name: Mdc1

    基因ID

    240087

    NCBI登录号

    NP_001010833

    UniProt

    Q5PSV9
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