MDC1 抗体 (N-Term)
Quick Overview for MDC1 抗体 (N-Term) (ABIN6657611)
抗原
See all MDC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- N-Term
-
Supplier Product No.
- 200-301-g12
-
Supplier
- Rockland
-
原理
- Mdc1 Antibody
-
交叉反应 (详细)
- A BLAST analysis was used to suggest cross-reactivity with MDC1 from Human, Mouse, Chimpanzee, and Bovine based on 100 % homology with the immunizing sequence.
-
纯化方法
- Anti-MDC1 Antibody was purified by Protein G chromatography.
-
过滤
- Sterile filtered
-
免疫原
- MDC1 Antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to mouse MDC1 at and around the N-terminus region.
-
亚型
- IgG1
-
-
-
-
应用备注
- Optional[Neutralization_Dilution]: User Optimized
-
说明
-
Anti-MDC1 Antibody is suitable for use in WB and IF microscopy. Expect a band approximately ~184kDa corresponding to specific lysates. Specific conditions for reactivity should be optimized by the end user.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
- MDC1 (Mdc1 (MDC1))
-
别名
- MDC1
-
背景
-
Synonyms: Nuclear factor with BRCT domains1, mediator of DNA damage checkpoint 1, Kiaa0170
Background: MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.
Gene Name: Mdc1
-
基因ID
- 240087
-
NCBI登录号
- NP_001010833
-
UniProt
- Q5PSV9
抗原
-