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Lamin B1 抗体 (C-Term)

This anti-Lamin B1 antibody is a 兔 多克隆 antibody detecting Lamin B1 in WB 和 IHC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
Rockland
产品编号 ABIN6657537
Supplier Product No.: 600-401-p62
发货至: 中国

Quick Overview for Lamin B1 抗体 (C-Term) (ABIN6657537)

抗原

See all Lamin B1 (LMNB1) 抗体
Lamin B1 (LMNB1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Lamin B1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    Supplier Product No.

    600-401-p62

    Supplier

    Rockland

    原理

    Lamin B1 Antibody

    交叉反应 (详细)

    Anti-Lamin B1 antibody is directed against human Lamin B1 protein.

    纯化方法

    The product was affinity purified from monospecific antiserum by immunoaffinity purification.

    免疫原

    Lamin B1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human Lamin B1.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry_Dilution: 0.5-1 μg/mL

    Western_Blot_Dilution: 0.1-0.5 μg/mL

    Other: Immunocytochemistry: 0.5-1 μg/mL

    说明

    Anti-Lamin B1 is tested for Immunohistochemistry-P, -F, Immunocytochemistry, and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~66.4 kDa corresponding to the appropriate cell lysate or extract. WB tested in Human, Mouse, Rat, IHC-P (heat) and IHC-F in human and rat, ICC in human, and ICC/IF in human.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 100 μL

    缓冲液

    Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

    Stabilizer: 5 mg BSA

    Preservative: 0.05 mg Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • Mastej, Axen, Wary, Minshall, Wary: "A requirement for Krüppel Like Factor-4 in the maintenance of endothelial cell quiescence." in: Frontiers in cell and developmental biology, Vol. 10, pp. 1003028, (2022) (PubMed).

  • 抗原

    Lamin B1 (LMNB1)

    别名

    Lamin B1

    背景

    Synonyms: LMNB1, LMN2, LMNB, Lamin B1 antibody

    Background: Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. This antibody is suitable for researchers interested in chromatin antibody research.

    Gene Name: LMNB1

    基因ID

    4001

    NCBI登录号

    NP_001172028.11

    UniProt

    P20700

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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