CCR6 抗体 (C-Term)
Quick Overview for CCR6 抗体 (C-Term) (ABIN6657519)
抗原
See all CCR6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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Supplier Product No.
- 600-401-p78
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Supplier
- Rockland
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原理
- CCR6 Antibody
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交叉反应 (详细)
- Anti-CCR6 antibody is directed against human CCR6 protein.
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- CCR6 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human CCR6.
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亚型
- IgG
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应用备注
- Optional[Neutralization_Dilution]: 0.5 μg/mL
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说明
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Anti-CCR6 is tested for Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~42.5 kDa corresponding to the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
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缓冲液
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Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide
Stabilizer: 5 mg BSA
Preservative: 0.05 mg Thimerosal -
储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
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别名
- CCR6
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背景
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Synonyms: Chemokine receptor-like 3,
Background: CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis. This antibody is suitable for researchers interested in cell signaling and neuroscience research.
Gene Name: CCR6
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基因ID
- 1235
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NCBI登录号
- NP_004358
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UniProt
- P51684
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途径
- cAMP Metabolic Process
抗原
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