ITGA3 抗体 (N-Term)
Quick Overview for ITGA3 抗体 (N-Term) (ABIN6657511)
抗原
See all ITGA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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Supplier Product No.
- 600-401-r13
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Supplier
- Rockland
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原理
- ITGA3 Antibody
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交叉反应 (详细)
- Anti-ITGA3 antibody is directed against human ITGA3 protein.
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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免疫原
- ITGA3 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the N-terminal of human ITGA3.
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亚型
- IgG
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应用备注
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Immunohistochemistry_Dilution: 2-5 μg/mL
Flow_Cytometry_Dilution: 1-3 μg/1x10^6 cells
IF_Microscopy_Dilution: 5 μg/mL
Western_Blot_Dilution: 0.1-0.5 μg/mL
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说明
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Anti-ITGA3 is tested for Immunohistochemistry -P, ICC/IF, Flow Cytometry, and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~116.6 kDa corresponding to the appropriate cell lysate or extract. 0.05 mg sodium azide and 0.05 mg Thimerosal have been added as preservatives.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 100 μL
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缓冲液
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Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide
Stabilizer: 5 mg BSA
Preservative: 0.05 mg Thimerosal -
储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- ITGA3 (Integrin, alpha 3 (ITGA3))
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别名
- ITGA3
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背景
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Synonyms: CD49 antigen-like family member C,FRP-2,Galactoprotein B3,
Background: ITGA3(INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit.A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis. This antibody is suitable for researchers interested in cancer research.
Gene Name: ITGA3
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基因ID
- 3675
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NCBI登录号
- NP_002195
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UniProt
- P26006
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途径
- CXCR4-mediated Signaling Events, Integrin Complex
抗原
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