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Paxillin 抗体 (AA 305-559)

Rockland 200-301-p44 PXN 适用: 小鸡 WB, ELISA 宿主: 小鼠 Monoclonal PXC-10 unconjugated
Rockland
产品编号 ABIN6657483
Supplier Product No.: 200-301-p44
发货至: 中国
  • 抗原 See all Paxillin (PXN) 抗体
    Paxillin (PXN)
    抗原表位
    • 32
    • 31
    • 22
    • 16
    • 9
    • 9
    • 9
    • 6
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    AA 305-559
    适用
    • 209
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    • 7
    • 5
    • 4
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    • 3
    • 1
    • 1
    • 1
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    • 1
    小鸡
    宿主
    • 202
    • 24
    • 1
    小鼠
    克隆类型
    • 185
    • 42
    单克隆
    标记
    • 118
    • 10
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    This Paxillin antibody is un-conjugated
    应用范围
    • 162
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    • 24
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    Western Blotting (WB), ELISA
    Supplier Product No.
    200-301-p44
    Supplier
    Rockland
    原理
    Paxillin Antibody
    交叉反应 (详细)
    This product reacts with human, mouse, rat, and chicken.
    纯化方法
    Anti-Paxillin antibody was purified from mouse ascites by protein A chromatography.
    免疫原
    Paxillin antibody was produced in mice by repeated immunizations with recombinant protein corresponding to the C-terminal part of chicken paxillin (amino acids 305-559).
    克隆位点
    PXC-10
    亚型
    IgG1
    Top Product
    Discover our top product PXN Primary Antibody
  • 应用备注

    ELISA_Dilution: 1:20,000

    Western_Blot_Dilution: 1-2 μg/mL

    Other: ICC: 1:100-1:500

    说明

    Anti-Paxillin is useful for Immunocytochemistry and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~64.5 kDa corresponding to the appropriate cell lysate or extract.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式

    Reconstitution_Buffer: Neutral PBS

    Reconstitution_Volume: 1.0 mL

    缓冲液

    Buffer: 1.2 % sodium acetate

    Stabilizer: 2 mg BSA

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    有效期
    12 months
  • 抗原
    Paxillin (PXN)
    别名
    Paxillin (PXN 产品)
    背景

    Synonyms: Paxillin antibody, PXN

    Background: The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68- kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells. This antibody is suitable for researchers interested in growth factors and signal trasduction.

    Gene Name: PXN

    基因ID
    5829
    NCBI登录号
    NP_001074324
    UniProt
    P49023
    途径
    MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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