ATRIP 抗体 (pSer239)
Quick Overview for ATRIP 抗体 (pSer239) (ABIN6657444)
抗原
See all ATRIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer239
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Supplier Product No.
- 600-401-w95
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Supplier
- Rockland
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原理
- ATRIP Phospho S239 Antibody
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交叉反应 （详细）
- Anti-ATRIP pS239 Antibody is directed against human ATRIP protein phosphorylated at S239.
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纯化方法
- The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
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过滤
- Sterile filtered
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免疫原
- Anti-Phospho-Ser239 ATRIP Antibody was produced from rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser239 of human ATRIP conjugated to KLH.
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亚型
- IgG
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anti-ATR Interacting Protein (ATRIP) (AA 42-309) antibody
ATRIP 适用: 人, 犬 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 5E7 unconjugated
anti-ATR Interacting Protein (ATRIP) (N-Term) antibodyATRIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (pSer224) antibodyATRIP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (pSer68) antibodyATRIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (AA 1-260) antibodyATRIP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (AA 1-260) antibodyATRIP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) antibodyATRIP 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (Tyr783) antibodyATRIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (pSer224) antibodyATRIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATR Interacting Protein (ATRIP) (AA 42-309) antibodyATRIP 适用: 人 WB 宿主: 小鼠 Monoclonal 1G6 unconjugated
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应用备注
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ELISA_Dilution: 1:5,000
Western_Blot_Dilution: 1:500
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说明
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Anti-ATRIP Phospho-Ser239 Antibody is tested for WB. Expect a band at approximately ~86 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user. The antibody also recognizes a band at ~32k.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
Preservative: None -
储存液
- Without preservative
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储存条件
- -20 °C
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储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
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有效期
- 12 months
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- ATRIP (ATR Interacting Protein (ATRIP))
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别名
- ATRIP
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背景
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Synonyms: ATM, Rad3-related-interacting protein, ATR-interacting protein
Background: ATRIP, ATR interacting protein, binds to ATR to regulate ATR expression, and is an essential component of the DNA damage checkpoint pathway (Cortez et al, 2001). ATR is recruited to DNA lesions in part through its association with ATRIP, which in turn interacts with the single-stranded DNA binding protein RPA (Ball et al, 2007). DNA replication forks may stall as a result of DNA damage causing phosphorylation of several proteins, including BRCA1 when colocalizing with ATR/ATRIP complex and RPA (Venere et al, 2007). The DNA replication fork stall coincides with BRCA1 directly phosphorylating ATRIP at ser239. ATRIP pS239 Antibody is ideal for researchers interested in cancer research.
Gene Name: ATRIP
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基因ID
- 84126
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NCBI登录号
- NP_001257951
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UniProt
- Q8WXE1
抗原
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