TLR5 抗体
Quick Overview for TLR5 抗体 (ABIN6656728)
抗原
See all TLR5 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 200-401-i28
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Supplier
- Rockland
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原理
- TLR5 Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with Anti-TLR5 from human, rat and mouse based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-TLR5 Antibody was purified by Protein G chromatography.
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免疫原
- TLR5 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a KLH-conjugated peptide corresponding to internal amino acids on human TLR5 protein.
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亚型
- IgG
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anti-Toll-Like Receptor 5 (TLR5) (AA 325-644) antibody
TLR5 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 693-858) antibodyTLR5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 303-514) antibodyTLR5 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 693-858) antibodyTLR5 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 8-1# unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 682-850) antibodyTLR5 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 700-800) antibodyTLR5 适用: 人, 小鼠 WB, IHC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 19D759-2 unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 701-810) antibodyTLR5 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 46-205) antibodyTLR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 300-350) antibodyTLR5 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 517-634) antibodyTLR5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A11 unconjugated
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应用备注
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Immunohistochemistry_Dilution: 10 μg/mL (paraffin)
Flow_Cytometry_Dilution: 1-2 μg/10^6 cells
Western_Blot_Dilution: 1-3 μg/mL
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说明
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Anti-TLR5 Antibody is tested for use in WB, Flow, Flow-CS, IHC, and IHC-P. Expect a band approximately 97kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.05 % (w/v) Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- TLR5 (Toll-Like Receptor 5 (TLR5))
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别名
- TLR5
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背景
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Synonyms: TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3
Background: Anti-TLR5 Antibody detects human TLR5. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Thirteen homologs of TLRs (TLR1-13) have been described. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens. Anti-TLR5 Antibody is ideal for investigator involved in cytokine and growth factor research.
Gene Name: TLR5
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基因ID
- 7100
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NCBI登录号
- NP_003259
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UniProt
- O60602
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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