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TLR9 抗体

TLR9 适用: 人 WB, IHC, FACS 宿主: 小鼠 Monoclonal 26C593-2 unconjugated
产品编号 ABIN6656659
发货至: 中国
  • 抗原 See all TLR9 抗体
    TLR9 (Toll-Like Receptor 9 (TLR9))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This TLR9 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Anti-TLR9 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TLR9 from monkey based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TLR9 from other sources has not been determined.
    免疫原

    Immunogen: TLR9 Antibody was produced in mice prepared repeated immunizations with amino acids corresponding to an internal sequence of human TLR9 isoform A protein.

    Immunogen Type: Peptide

    克隆位点
    26C593-2
    亚型
    IgG1
    Top Product
    Discover our top product TLR9 Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: 10-20 μg/mL (frozen)

    Application Note: Anti-TLR9 Antibody is suitable for use in CM, Flow (CS), Flow (I), IF/ICC, IHC (frozen), IHC (p) and WB. Expect a band approximately 113 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    Flow Cytometry Dilution: 0.1-2 μg/10^6 cells

    Western Blot Dilution: 1-5 μg/mL

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.05 % BSA

    0.05 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • 抗原
    TLR9 (Toll-Like Receptor 9 (TLR9))
    别名
    TLR9 (TLR9 产品)
    别名
    CD289 antibody, toll like receptor 9 antibody, toll-like receptor 9 antibody, TLR9 antibody, Tlr9 antibody
    背景

    Synonyms: Toll-like receptor 9

    Background: Anti-TLR9 CD289 Antibody detects human TLR9 CD289. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. By using a BLAST search, a cDNA coding for TLR9 has been identified and subsequently isolated. Gene knockout experiments suggest that TLR9 acts as a receptor for unmethylated CpG dinucleotides in the bacterial DNA. Human and mouse TLR9 share an overall amino-acid identity of 75.5 % . TLR9 is highly expressed in spleen. Anti-TLR9 CD289 Antibody is ideal for investigators involved in cytokines and growth factor research.

    Gene Name: TLR9

    基因ID
    54106
    NCBI登录号
    NP_059138
    UniProt
    Q9NR96
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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