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TLR9 抗体

This 小鼠 单克隆 anti-TLR9 antibody (Clone 26C593-2) specifically detects TLR9 in WB, IHC, FACS, IP, IF 和 DB. The antibody is reactive with 人 samples.
Rockland
产品编号 ABIN6656659
Supplier Product No.: 200-301-i31
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TLR9 抗体 (ABIN6656659)

抗原

See all TLR9 抗体
TLR9 (Toll-Like Receptor 9 (TLR9))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TLR9 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Dot Blot (DB)

克隆位点

26C593-2
  • Supplier Product No.

    200-301-i31

    Supplier

    Rockland

    原理

    TLR9 Antibody

    交叉反应 (详细)

    A BLAST analysis was used to suggest cross-reactivity with Anti-TLR9 from monkey based on 100 % homology with the immunizing sequence.

    纯化方法

    Anti-TLR9 Antibody was purified by Protein G chromatography.

    免疫原

    TLR9 Antibody was produced in mice prepared repeated immunizations with amino acids corresponding to an internal sequence of human TLR9 isoform A protein.

    亚型

    IgG1 kappa
  • 应用备注

    Immunohistochemistry_Dilution: 10-20 μg/mL (frozen)

    Flow_Cytometry_Dilution: 0.1-2 μg/10^6 cells

    Western_Blot_Dilution: 1-5 μg/mL

    说明

    Anti-TLR9 Antibody is tested for use in WB, DB, ELISA, Flow, Flow-IC, ICC/IF, IHC, IHC-P, and IP. Expect a band approximately 113kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.05 % BSA

    Preservative: 0.05 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    TLR9 (Toll-Like Receptor 9 (TLR9))

    别名

    TLR9

    背景

    Synonyms: Toll-like receptor 9

    Background: Anti-TLR9 CD289 Antibody detects human TLR9 CD289. The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. By using a BLAST search, a cDNA coding for TLR9 has been identified and subsequently isolated. Gene knockout experiments suggest that TLR9 acts as a receptor for unmethylated CpG dinucleotides in the bacterial DNA. Human and mouse TLR9 share an overall amino-acid identity of 75.5 % . TLR9 is highly expressed in spleen. Anti-TLR9 CD289 Antibody is ideal for investigators involved in cytokines and growth factor research.

    Gene Name: TLR9

    基因ID

    54106

    NCBI登录号

    NP_059138

    UniProt

    Q9NR96

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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