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TNFAIP3 抗体 (C-Term)

This anti-TNFAIP3 antibody is a 小鼠 单克隆 antibody detecting TNFAIP3 in WB, IHC, IF, IP 和 FACS. Suitable for 人.
Rockland
产品编号 ABIN6655643
Supplier Product No.: 200-301-h52
发货至: 中国

Quick Overview for TNFAIP3 抗体 (C-Term) (ABIN6655643)

抗原

See all TNFAIP3 抗体
TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))

适用

  • 57
  • 31
  • 25
  • 4
  • 1

宿主

  • 52
  • 4
  • 1
小鼠

克隆类型

  • 43
  • 14
单克隆

标记

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  • 2
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  • 2
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  • 1
  • 1
  • 1
  • 1
  • 1
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This TNFAIP3 antibody is un-conjugated

应用范围

  • 22
  • 15
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  • 7
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

克隆位点

59A426
  • 抗原表位

    • 15
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
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    • 1
    C-Term

    Supplier Product No.

    200-301-h52

    Supplier

    Rockland

    原理

    A20 Antibody

    交叉反应 (详细)

    A BLAST analysis was used to suggest cross-reactivity with Anti-A20 from Human, Mouse and rat based on 100 % homology with the immunizing sequence.

    纯化方法

    Anti-A20 Antibody was purified by Protein G chromatography.

    免疫原

    A20 Antibody was produced in mice by repeated immunizations with recombinant human A20 protein at the c-terminus.

    亚型

    IgG1 kappa
  • 应用备注

    Immunoprecipitation_Dilution: 1-2 μg/mL

    Western_Blot_Dilution: 2-4 μg/mL

    说明

    Anti-A20 antibody is tested for use in WB, Flow, Flow-IC, ICC/IF, IHC, IHC-P, and IP. Expect a band approximately 90kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.05 % BSA

    Preservative: 0.05 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))

    别名

    TNFAIP3

    背景

    Synonyms: OTUD7C, Tumor necrosis factor alpha-induced protein 3, TNF alpha-induced protein 3, OTU domain-containing protein 7C, A20p50, A20p37

    Background: Anti-A20 antibody detects human A20. A20 (TNFAIP3) is an important regulator of proinflammatory signaling pathways, including NK-kB sginaling. A20 is upregulated through NF-kB (p50/p55) activation, and subsequently down regulates NF-kB through its dual function as a deubiquitinase and ubiquitin ligase. The A20 monoclonal antibody has been instrumental in discovering various nuances of NF-kB regulation and key to defining A20 biology. Anti-A20 antibody is ideal for investigators involved in NFkappaB and Signaling research.

    Gene Name: TNFAIP3

    基因ID

    7128

    NCBI登录号

    NP_001257436

    UniProt

    P21580

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response
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