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KDM1B 抗体 (Internal Region, N-Term)

KDM1B 适用: 人 ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6655594
发货至: 中国
  • 抗原 See all KDM1B 抗体
    KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))
    抗原表位
    • 15
    • 6
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    • 1
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    • 1
    Internal Region, N-Term
    适用
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    • 17
    • 2
    • 2
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    宿主
    • 37
    • 10
    克隆类型
    • 35
    • 12
    多克隆
    标记
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    • 2
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    This KDM1B antibody is un-conjugated
    应用范围
    • 20
    • 20
    • 13
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    • 4
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    ELISA
    交叉反应 (详细)
    Cross reactivity with KDM1B from other species not tested.
    纯化方法
    Anti-KDM1B Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
    免疫原

    Immunogen: Anti-KDM1B Antibody was produced in rabbits by repeated immunizations with two different synthetic peptides containing a sequence from the N-terminus and internal region of the human KDM1B protein.

    Immunogen Type: Peptide

    Top Product
    Discover our top product KDM1B Primary Antibody
  • 应用备注

    Application Note: Anti-KDM1B Antibody is suitable for ELISA. Specific conditions for reactivity should be optimized by the end user.

    ELISA Dilution: 1:500

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    0.01 % (w/v) Sodium Azide

    Stabilizer: None

    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • 抗原
    KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))
    别名
    KDM1B (KDM1B 产品)
    别名
    AOF1 antibody, C6orf193 antibody, LSD2 antibody, bA204B7.3 antibody, dJ298J15.2 antibody, 4632428N09Rik antibody, AI482520 antibody, Aof1 antibody, lysine demethylase 1B antibody, lysine-specific histone demethylase 1B antibody, lysine (K)-specific demethylase 1B antibody, KDM1B antibody, LOC577549 antibody, kdm1b antibody, Kdm1b antibody
    背景

    Synonyms: Lysine-specific histone demethylase 1B, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2, AOF1, C6orf193, LSD2

    Background: KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Anti-KDM1B is ideal for research in Epigenetics and Gene Expression.

    Gene Name: KDM1B

    基因ID
    221656
    NCBI登录号
    NP_694587
    UniProt
    Q8NB78
    途径
    Warburg Effect
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