KDM1B 抗体 (Internal Region, N-Term)
Quick Overview for KDM1B 抗体 (Internal Region, N-Term) (ABIN6655594)
抗原
See all KDM1B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region, N-Term
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Supplier Product No.
- 100-401-w43
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Supplier
- Rockland
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原理
- KDM1B Antibody
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交叉反应 （详细）
- Cross reactivity with KDM1B from other species not tested.
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纯化方法
- Anti-KDM1B Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
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过滤
- Sterile filtered
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免疫原
- Anti-KDM1B Antibody was produced in rabbits by repeated immunizations with two different synthetic peptides containing a sequence from the N-terminus and internal region of the human KDM1B protein.
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 1B (KDM1B) (AA 6-129) antibody
KDM1B 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5E10C1 unconjugated
anti-Lysine (K)-Specific Demethylase 1B (KDM1B) (AA 451-544) antibodyKDM1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 1B (KDM1B) (AA 38-73), (N-Term) antibodyKDM1B 适用: 人 WB 宿主: 兔 Polyclonal RB49895 unconjugated
anti-Lysine (K)-Specific Demethylase 1B (KDM1B) (N-Term) antibodyKDM1B 适用: 人, 小鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 1B (KDM1B) (N-Term) antibodyKDM1B 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 1B (KDM1B) antibodyKDM1B 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- Optional[Neutralization_Dilution]: 1:500
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说明
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Anti-KDM1B Antibody has been tested by ELISA. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: None
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))
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别名
- KDM1B
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背景
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Synonyms: Lysine-specific histone demethylase 1B, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2, AOF1, C6orf193, LSD2
Background: KDM1B is a histone demethylase that demethylates lysine 4 of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. KDM1B is able to demethylate both mono- and di-methylated lysine 4 of histone H3, but has no effect on tri-methylated lysine 4, mono-, di- or tri-methylated lysine 9, mono-, di- or tri-methylated lysine 27, mono-, di- or tri-methylated lysine 36 of histone H3, or on mono-, di- or tri-methylated lysine 20 of histone H4. KDM1B is also required for de novo DNA methylation of a subset of imprinted genes during oogenesis. It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Anti-KDM1B is ideal for research in Epigenetics and Gene Expression.
Gene Name: KDM1B
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基因ID
- 221656
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NCBI登录号
- NP_694587
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UniProt
- Q8NB78
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途径
- Warburg Effect
抗原
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