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- 抗原 See all RIPK3 抗体
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RIPK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Anti-Receptor-interacting serine-threonine kinase 3 Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-Receptor-interacting serine-threonine kinase 3 from human and chimpanzee based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Receptor-interacting serine-threonine kinase 3 from other sources has not been determined.
- 免疫原
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Immunogen: Receptor-interacting serine-threonine kinase 3 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to amino acids near the c-terminus of human Receptor-interacting serine/threonine-protein kinase 3.
Immunogen Type: Peptide
- 亚型
- IgG
- Top Product
- Discover our top product RIPK3 Primary Antibody
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anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-120) antibody
RIPK3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (N-Term) antibodyRIPK3 适用: 人, 小鼠, 大鼠, Cow, Pig, 马, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 61-91) antibodyRIPK3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 16-239) antibodyRIPK3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 489-518) antibodyRIPK3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) antibodyRIPK3 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-217) antibodyRIPK3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-518) antibodyRIPK3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-120) antibodyRIPK3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 168-217) antibodyRIPK3 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry Dilution: 10 μg/mL
Application Note: Anti-Receptor-interacting serine-threonine kinase 3 antibody is suitable for use in IHC (p) and WB. Expect a band approximately 56 kDa (isoform 1) and 27 kDa (isoform 2) on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 3-7 μg/mL
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
0.05 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
- 别名
- Receptor-interacting serine-threonine kinase 3 (RIPK3 产品)
- 别名
- RIPK3 antibody, RIP3 antibody, 2610528K09Rik antibody, AW107945 antibody, Rip3 antibody, Hcyp2 antibody, receptor interacting serine/threonine kinase 3 antibody, receptor interacting serine/threonine kinase 3 S homeolog antibody, receptor-interacting serine-threonine kinase 3 antibody, RIPK3 antibody, ripk3.S antibody, Ripk3 antibody
- 背景
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Synonyms: RIP3, Receptor-interacting serine/threonine-protein kinase 3, 2.7.11.1, RIP-like protein kinase 3, Receptor-interacting protein 3
Background: Anti-Receptor-interacting serine-threonine kinase 3 antibody detects human RIP3. RIP3 is a novel member of RIP Ser/Thr kinase family. It is a potent inducer of apoptosis and is an important component of TNFR1 signaling complex. RIP3 consists of an N-terminal RIP-like-Kinase domain and a unique, non-homologous C-terminus responsible for caspase activation and apoptosis induction. RIP3 is expressed in multiple tissues including hematopoietic cells and plays a functional role in the regulation of apoptosis and NF-kB signaling. It is recruited to the TNFR1 signaling complex in a RIP-dependant manner where it induces apoptosis by activating caspases and/or inhibiting TNFR1-induced NF-kB activation. RIP3 negatively regulates the TLR3-Trif mediated NF-kB signaling pathway by competing with the binding of Trif to RIP1. The human RIP3 gene is localized in the chromosomal region 14q11.2. Anti-Receptor-interacting serine-threonine kinase 3 Antibody is ideal for investigators involved in apoptosis and NFkappaB research.
Gene Name: RIPK3
- 基因ID
- 11035
- NCBI登录号
- NP_006862
- UniProt
- Q9Y572
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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