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VEGFR2/CD309 抗体 (Extracellular Domain)

The 小鼠 单克隆 anti-VEGFR2/CD309 antibody is suitable to detect VEGFR2/CD309 in samples from 人. It has been validated for IHC.
Rockland
产品编号 ABIN6655552
Supplier Product No.: 200-301-p49
发货至: 中国
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Quick Overview for VEGFR2/CD309 抗体 (Extracellular Domain) (ABIN6655552)

抗原

See all VEGFR2/CD309 (VEGFR2) 抗体
VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

适用

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小鼠

克隆类型

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单克隆

标记

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This VEGFR2/CD309 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)

克隆位点

KDR-1
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    Extracellular Domain

    Supplier Product No.

    200-301-p49

    Supplier

    Rockland

    原理

    VEGFR2 Antibody

    交叉反应 (详细)

    This product reacts with human.

    纯化方法

    Anti-VEGFR2 antibody was purified from mouse ascites by protein A chromatography.

    免疫原

    VEGFR2 antibody was produced in mice by repeated immunizations with recombinant protein corresponding to human extracellular domain of VEGFR-2 (KDR).

    亚型

    IgG1
  • 应用备注

    Optional[Neutralization_Dilution]: 1:100-1:500

    说明

    Anti-VEGFR2 is tested for Immunohistochemistry-F. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~151.5 kDa corresponding to the appropriate cell lysate or extract.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitution_Buffer: Neutral PBS

    Reconstitution_Volume: 1.0 mL

    缓冲液

    Buffer: 1.2 % sodium acetate

    Stabilizer: 2 mg BSA

    Preservative: 0.01 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    有效期

    12 months
  • 抗原

    VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

    别名

    VEGFR2

    背景

    Synonyms: CD309, VEGFR, FLK1, VEGFR2, TYROSINE KINASE GROWTH FACTOR RECEPTOR, FLK1, MOUSE, HOMOLOG OF, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1

    Background: VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. The importance of VEGF and its receptor system in tumor growth and intervention in this system may provide promising approaches to cancer therapy. VEGF receptor 2 is a member of a receptor tyrosine kinase family.Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. This antibody is suitable for researchers interested in cell signaling and cancer research.

    Gene Name: KDR

    基因ID

    3791

    NCBI登录号

    NP_002244

    UniProt

    P35968

    途径

    RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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