VEGFR2/CD309 抗体 (Extracellular Domain)
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Quick Overview for VEGFR2/CD309 抗体 (Extracellular Domain) (ABIN6655552)
抗原
See all VEGFR2/CD309 (VEGFR2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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Supplier Product No.
- 200-301-p49
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Supplier
- Rockland
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原理
- VEGFR2 Antibody
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交叉反应 (详细)
- This product reacts with human.
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纯化方法
- Anti-VEGFR2 antibody was purified from mouse ascites by protein A chromatography.
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免疫原
- VEGFR2 antibody was produced in mice by repeated immunizations with recombinant protein corresponding to human extracellular domain of VEGFR-2 (KDR).
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亚型
- IgG1
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应用备注
- Optional[Neutralization_Dilution]: 1:100-1:500
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说明
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Anti-VEGFR2 is tested for Immunohistochemistry-F. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~151.5 kDa corresponding to the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Neutral PBS
Reconstitution_Volume: 1.0 mL
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缓冲液
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Buffer: 1.2 % sodium acetate
Stabilizer: 2 mg BSA
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
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别名
- VEGFR2
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背景
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Synonyms: CD309, VEGFR, FLK1, VEGFR2, TYROSINE KINASE GROWTH FACTOR RECEPTOR, FLK1, MOUSE, HOMOLOG OF, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1
Background: VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. The importance of VEGF and its receptor system in tumor growth and intervention in this system may provide promising approaches to cancer therapy. VEGF receptor 2 is a member of a receptor tyrosine kinase family.Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. This antibody is suitable for researchers interested in cell signaling and cancer research.
Gene Name: KDR
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基因ID
- 3791
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NCBI登录号
- NP_002244
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UniProt
- P35968
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途径
- RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
抗原
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