KDM4A 抗体 (Internal Region)
Quick Overview for KDM4A 抗体 (Internal Region) (ABIN6655514)
抗原
See all KDM4A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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Supplier Product No.
- 600-401-x45
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Supplier
- Rockland
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原理
- JMJD2A Antibody
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交叉反应 （详细）
- Cross reactivity with other species was not tested.
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纯化方法
- Anti-JMJD2a Antibody was purified by affinity purification.
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过滤
- Sterile filtered
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免疫原
- Anti-JMJD2a Antibody was produced in rabbits by repeated immunizations with a synthetic peptide from human JMJD2a containing a sequence from the internal part of the protein.
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 141-310) antibody
KDM4A 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 932-1057) antibodyKDM4A 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6E10G4 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 585-815) antibodyKDM4A 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) antibodyKDM4A 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 5H1 unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (AA 127-364) antibodyKDM4A 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) antibodyKDM4A 适用: 人 DB, ICC 宿主: 小鼠 Monoclonal 3559D5a unconjugated
anti-Lysine (K)-Specific Demethylase 4A (KDM4A) (Center) antibodyKDM4A 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA_Dilution: 1:100 - 1:500
Western_Blot_Dilution: 1:500
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说明
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Anti-JMJD2a Antibody is tested for ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 121 kDa in the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300 -
储存液
- ProClin, Sodium azide
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注意事项
- This product contains Sodium azide and ProClin: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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别名
- JMJD2a
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背景
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Synonyms: Lysine-specific demethylase 4A, JmjC domain-containing histone demethylation protein 3A, Jumonji domain-containing protein 2A, JHDM3A, JMJD2, KIAA0677
Background: JMJD2a, belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2a specifically demethylates the trimethylated K9 and K36 of histone H3, thereby converting these lysines to the dimethylated form. It has no activity towards H3K4, H3K27 and H4K20, or to the mono- and dimethylated H3K9 and H3K36. JMJD2a plays a role in the transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. Anti-JMJD2a Antibody is ideal for research in Chromatin Remodeling, Gene Expression and Epigenetics.
Gene Name: KDM4A
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基因ID
- 9682
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NCBI登录号
- NP_055478
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UniProt
- O75164
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途径
- Warburg Effect
抗原
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