CDC6 抗体
Quick Overview for CDC6 抗体 (ABIN6655469)
抗原
See all CDC6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-301-p29
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Supplier
- Rockland
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原理
- CDC6 Antibody
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交叉反应 （详细）
- This product reacts with human.
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纯化方法
- Anti-CDC6 antibody was purified from mouse ascites by protein A chromatography.
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免疫原
- CDC6 antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to human Cdc6.
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亚型
- IgG1
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anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (AA 1-560) antibody
CDC6 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (AA 1-326) antibodyCDC6 适用: 人, 小鼠 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (AA 1-141) antibodyCDC6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) antibodyCDC6 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (AA 147-549) antibodyCDC6 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (AA 434-533) antibodyCDC6 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (Internal Region) antibodyVerified CDC6 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (pSer54) antibodyCDC6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7524 unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (N-Term), (pSer54) antibodyCDC6 适用: 人, 小鼠, 大鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6) (AA 20-69), (pSer54) antibodyCDC6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA_Dilution: 1:20,000
Western_Blot_Dilution: 1-2 μg/mL
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说明
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Anti-CDC6 is tested for Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~62.7 kDa corresponding to the appropriate cell lysate or extract.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
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Reconstitution_Buffer: Neutral PBS
Reconstitution_Volume: 1.0 mL
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缓冲液
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Buffer: 1.2 % sodium acetate
Stabilizer: 2 mg BSA
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- CDC6 (Cell Division Cycle 6 Homolog (S. Cerevisiae) (CDC6))
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别名
- CDC6
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背景
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Synonyms: CDC18L, HsCdc18, p62(cdc6), CELL DIVISION CYCLE 18, S. POMBE, HOMOLOG-LIKE, CDC6 (cell division cycle 6, S. cerevisiae) homolog, CELL CYCLE CONTROLLER CDC6, CDC6-related protein, Cdc18-related protein
Background: In yeasts, Cdc6 (Saccharomyces cerevisiae) and Cdc18 (Schizosaccharomyces pombe) associate with the origin recognition complex (ORC) proteins to render cells competent for DNA replication. Cdc6 is overexpressed in human cancers, where it has a critical regulatory role in addition to DNA replication. Yan et al. (1998) showed that Cdc6 is expressed selectively in proliferating but not quiescent mammalian cells, both in culture and within tissues in intact animals. During the transition from a growth-arrested to a proliferative state, transcription of mammalian Cdc6 is regulated by E2F proteins, as revealed by a functional analysis of the human Cdc6 promoter and by the ability of exogenously expressed E2F proteins to stimulate the endogenous Cdc6 gene. They conclude that expression of human Cdc6 is regulated in response to mitogenic signals though transcriptional control mechanisms involving E2F proteins, and that Cdc6 is required for initiation of DNA replication in mammalian cells. This antibody is suitable for researchers interested in cancer research and Cell Cycle research.
Gene Name: CDC6
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基因ID
- 990
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NCBI登录号
- NP_001245
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UniProt
- Q99741
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途径
- DNA Replication, Synthesis of DNA
抗原
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