TLR7 抗体
Quick Overview for TLR7 抗体 (ABIN6655379)
抗原
See all TLR7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
Supplier Product No.
- 200-301-i29
-
Supplier
- Rockland
-
原理
- TLR7 Antibody
-
交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with Anti-TLR7 from human based on 100 % homology with the immunizing sequence.
-
纯化方法
- Anti-TLR7 Antibody was purified by Protein G chromatography.
-
免疫原
- TLR7 Antibody was produced in mice prepared by repeated immunizations with an internal portion of human TLR7 recombinant protein.
-
亚型
- IgG1 kappa
-
-
anti-Toll-Like Receptor 7 (TLR7) (AA 30-230) antibody
TLR7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 1020-1047), (C-Term) antibodyTLR7 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 461-560) antibodyTLR7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 465-483) antibodyTLR7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) antibodyTLR7 适用: 人, 小鼠, 大鼠 WB, FACS, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 900-950) antibodyTLR7 适用: 人, 猴 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 27-126) antibodyTLR7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C9 unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 706-728) antibody (FITC)TLR7 适用: 人, 小鼠 FACS 宿主: 兔 Polyclonal FITC
anti-Toll-Like Receptor 7 (TLR7) (AA 890-1037) antibodyTLR7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 7 (TLR7) (AA 706-728) antibodyTLR7 适用: 人, 小鼠 WB, IHC, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Flow_Cytometry_Dilution: 1-2 μg/10^6 cells
Western_Blot_Dilution: 10 μg/mL
-
说明
-
Anti-TLR7 Antibody is tested for use in WB, Flow, Flow-IC, ICC/IF, and IHC. Expect a band approximately 121kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
- TLR7 (Toll-Like Receptor 7 (TLR7))
-
别名
- TLR7
-
背景
-
Synonyms: Toll-like receptor 7
Background: Anti-TLR7 Antibody detects human TLR7. TLR7 is a 1049 amino acid long highly conserved membrane protein belonging to the Toll-like receptor (TLR) family with 27 LRR (leucine-rich) repeats and a TIR domain. It plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 is activated by infections with single-stranded RNA viruses, including influenza virus and vesicular stomatitis virus (VSV). It is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8. It acts via MyD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Anti-TLR7 Antibody is ideal for investigators that are involved in cytokin and grow factor research.
Gene Name: TLR7
-
基因ID
- 51284
-
NCBI登录号
- NP_057646
-
UniProt
- Q9NYK1
-
途径
- TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
-
