CD11b 抗体 (PE)
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北京 101111
Quick Overview for CD11b 抗体 (PE) (ABIN6655311)
抗原
See all CD11b (ITGAM) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-308-n20
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Supplier
- Rockland
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原理
- CD11b Phycoerythrin Antibody
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交叉反应 （详细）
- Reactivity is observed against human CD11b, Baboon, Chimpanzee, Cynomolgus, Rhesus, and Swine.
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纯化方法
- Phycoerythrin conjugated CD11b Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD11b.
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过滤
- Sterile filtered
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免疫原
- Anti-CD11b Antibody (Monoclonal) was produced by repeated immunizations with CD11b antigen.
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亚型
- IgG1 kappa
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Labeling Ratio
- 1-2
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anti-Integrin alpha M (ITGAM) (AA 520-570) antibody
ITGAM 适用: 人, 小鼠, 大鼠 FACS 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 145-340) antibodyITGAM 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 77-180) antibodyITGAM 适用: 人, 小鼠, 大鼠 FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibodyITGAM 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB17991 unconjugated
anti-Integrin alpha M (ITGAM) (AA 31-160) antibodyITGAM 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 941-1074) antibodyITGAM 适用: 人 IHC, WB, StM 宿主: 小鼠 Monoclonal ITGAM-3340 unconjugated
anti-Integrin alpha M (ITGAM) (AA 941-1074) antibodyITGAM 适用: 人 IHC, WB, StM 宿主: 小鼠 Monoclonal ITGAM-3338 unconjugated
anti-Integrin alpha M (ITGAM) antibody (FITC)ITGAM 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-174 FITC
anti-Integrin alpha M (ITGAM) antibody (Biotin)ITGAM 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-174 Biotin
anti-Integrin alpha M (ITGAM) antibody (PE)ITGAM 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-174 PE
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应用备注
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Immunoprecipitation_Dilution: User Optimized
Flow_Cytometry_Dilution: 5μL/test/1x10e5 to 1x10e8 cells
IF_Microscopy_Dilution: User Optimized
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说明
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Anti-CD11b is tested for Flow Cytometry and is useful in Immunofluorescence and Immunoprecipitation. Researchers should determine optimal titers for applications that are not stated.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.1 % Gelatin
Preservative: 0.09 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
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有效期
- 6 months
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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别名
- CD11b
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背景
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Synonyms: Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b, CR3A
Background: The ICRF44 antibody reacts with human CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1, ICAM-2, ICAM-3 and ICAM-4 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.The ICRF44 antibody is widely used as a marker for CD11b expression on macrophages, granulocytes, and subsets of NK cells.
Gene Name: ITGAM
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基因ID
- 3684
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NCBI登录号
- NP_000623
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UniProt
- P11215
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途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
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