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CD11b 抗体 (FITC)

This anti-CD11b antibody is a 小鼠 单克隆 antibody detecting CD11b in FACS, IP 和 FM. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
Rockland
产品编号 ABIN6655310
Supplier Product No.: 200-302-n20
发货至: 中国

Quick Overview for CD11b 抗体 (FITC) (ABIN6655310)

抗原

See all CD11b (ITGAM) 抗体
CD11b (ITGAM) (Integrin alpha M (ITGAM))

适用

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小鼠

克隆类型

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单克隆

标记

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This CD11b antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

克隆位点

ICRF44
  • Supplier Product No.

    200-302-n20

    Supplier

    Rockland

    原理

    CD11b Fluorescein Antibody

    交叉反应 (详细)

    Reactivity is observed against human CD11b, Chimpanzee, Baboon, Cynomolgus, Rhesus, Common Marmoset, and Swine.

    纯化方法

    Fluorescein conjugated CD11b Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD11b.

    过滤

    Sterile filtered

    免疫原

    Anti-CD11b Antibody (Monoclonal) was produced by repeated immunizations with CD11b antigen.

    亚型

    IgG1 kappa

    Labeling Ratio

    4-6
  • 应用备注

    Immunoprecipitation_Dilution: User Optimized

    Flow_Cytometry_Dilution: 5 µL/1x10e6 cells or 100μL of whole blood

    IF_Microscopy_Dilution: User Optimized

    说明

    Anti-CD11b has been tested in Flow Cytometry and is useful for Immunofluorescence and Immunoprecipitation. Researchers should determine optimal titers for applications that are not stated.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.2 % BSA (w/v)

    Preservative: 0.09 % (w/v) Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.

    有效期

    6 months
  • Guo, Wang, Dong, Lv, Zhao, Jin, Guo, Wang, Cai, Sun, Zhou, Zhang, Chen, Yang, Ji, Xin, Li, Li, Fan: "Effects of Ginkgo biloba on Early Decompression after Spinal Cord Injury." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2020, pp. 6958246, (2020) (PubMed).

    Stewart, Thiel, Hogg: "Leukocyte integrins." in: Current opinion in cell biology, Vol. 7, Issue 5, pp. 690-6, (1996) (PubMed).

  • 抗原

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    别名

    CD11b

    背景

    Synonyms: Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b, CR3A

    Background: CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and Factor X.

    Gene Name: ITGAM

    基因ID

    3684

    NCBI登录号

    NP_000623

    UniProt

    P11215

    途径

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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