IFNAR1 抗体 (pSer535, pSer539)
Quick Overview for IFNAR1 抗体 (pSer535, pSer539) (ABIN6655258)
抗原
See all IFNAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer535, pSer539
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Supplier Product No.
- 600-401-d67
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Supplier
- Rockland
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原理
- Interferon alpha Receptor Type I phospho S535/phospho S539 Antibody
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交叉反应 （详细）
- Anti-Interferon alpha Receptor Type I pS535/pS539 Antibody is directed against human Interferon alpha Receptor Type I phosphorylated at positions S535/S539.
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纯化方法
- The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
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免疫原
- Anti-Interferon alpha Receptor Type I pS535/pS539 Antibody was produced by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser535/539.
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亚型
- IgG
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anti-Interferon alpha/beta Receptor 1 (IFNAR1) (AA 470-557) antibody
IFNAR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (AA 28-290) antibodyIFNAR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (AA 162-188) antibodyIFNAR1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21945 unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (pSer535), (pSer538) antibodyIFNAR1 适用: 人, 大鼠 ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (AA 300-350) antibodyIFNAR1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (pSer535), (pSer539) antibodyIFNAR1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (AA 28-127) antibodyIFNAR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (pSer535), (Ser539) antibodyIFNAR1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) antibodyIFNAR1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Interferon alpha/beta Receptor 1 (IFNAR1) (AA 162-188) antibodyIFNAR1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry_Dilution: 1:1000
Western_Blot_Dilution: 1:1000
Other: Dot Blot: 1:1000
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说明
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Anti-Interferon alpha Receptor Type I pS535/pS539 (Rabbit) antibody is suitable for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. The molecular weight of the IFNAR1 varies with cell line due to different levels of glycosylation in 293 and HeLa Cells, the mature form is approximately 110-130 kDa in size.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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有效期
- 12 months
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- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
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别名
- Interferon alpha Receptor Type I
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背景
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Synonyms: Interferon alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1
Background: Interferon alpha Receptor Type I pS535/pS539 Antibody detects Interferon alpha Receptor Type I phopshorylated at positions S535/S539. Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon-α Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1. Therefore, Interferon alpha Receptor Type I phospho S535/phospho S539 antibody is ideal for investigators involved in Cell Signaling, Virology, Immunology and Cancer Research.
Gene Name: IFNAR1
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基因ID
- 3454
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UniProt
- P17181
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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