GREM1 抗体
Quick Overview for GREM1 抗体 (ABIN6655147)
抗原
See all GREM1 抗体适用
宿主
克隆类型
标记
应用范围
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Supplier Product No.
- 200-401-h77
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Supplier
- Rockland
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原理
- Gremlin Antibody
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交叉反应 （详细）
- A BLAST analysis was used to suggest cross-reactivity with Anti-Gremlin from Human, Rat and Mouse based on 100 % homology with the immunizing sequence.
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纯化方法
- Anti-Gremlin Antibody was purified by Protein G chromatography.
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免疫原
- Gremlin Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the internal amino acid sequences within the Gremlin-1 human protein.
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亚型
- IgG
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anti-Gremlin 1 (GREM1) (AA 101-184) antibody
GREM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 147-175), (C-Term) antibodyGREM1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB2060 unconjugated
anti-Gremlin 1 (GREM1) (AA 26-184) antibodyGREM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 25-184) antibodyGREM1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 26-184) antibodyGREM1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Gremlin 1 (GREM1) (AA 25-184) antibodyGREM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 75-184) antibodyGREM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Gremlin 1 (GREM1) (AA 18-184) antibodyGREM1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 27-184) antibodyGREM1 适用: 小鸡 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Gremlin 1 (GREM1) (AA 147-175), (C-Term) antibodyGREM1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry_Dilution: 2.5-10 μg/mL (paraffin)
Western_Blot_Dilution: 1:500-1:1000
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说明
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Anti-Gremlin Antibody is tested for use in IHC (cryosections) and IHC-P. Specific conditions for reactivity should be optimized by the end user.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.05 % BSA
Preservative: 0.05 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- GREM1 (Gremlin 1 (GREM1))
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别名
- Gremlin
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背景
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Synonyms: CKTSF1B1, DAND2, DRM, Gremlin-1, Cell proliferation-inducing gene 2 protein, Cysteine knot superfamily 1, BMP antagonist 1, DAN domain family member 2, Down-regulated in Mos-transformed cells protein, Increased in high glucose protein 2
Background: Anti-Gremlin Antibody detects human Gremlin. In Xenopus, Gremlin belongs to a novel gene family that act as BMP antagonists in embryonic explants. The human homolog of Gremlin (CKTSF1B1) is localized on chromosome 15q13--> q15. DRM-specific mRNA is expressed in different tissues, including brain, ovary, intestine and colon. It has been suggested that down-regulation of Gremlin is associated with tumor progression, and support the hypothesis that Gremlin may play an important role during both neuroembryological development and carcinogenesis. Anti-Gremlin Antibody is ideal for investigators involved in NFkappaB, signaling, and cell cycle protein research.
Gene Name: GREM1
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基因ID
- 26585
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NCBI登录号
- NP_001178252
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UniProt
- O60565
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途径
- Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
抗原
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