CD80 抗体 (PE)
Quick Overview for CD80 抗体 (PE) (ABIN6655082)
抗原
See all CD80 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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Supplier Product No.
- 200-308-n74
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Supplier
- Rockland
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原理
- CD80 Phycoerythrin Antibody
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交叉反应 (详细)
- Reactivity is observed against human CD80.
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纯化方法
- Phycoerythrin conjugated CD80 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD80.
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过滤
- Sterile filtered
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免疫原
- Anti-CD80 Antibody (Monoclonal) was produced by repeated immunizations with CD80 antigen.
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亚型
- IgG1 kappa
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Labeling Ratio
- 1-2
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应用备注
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Immunohistochemistry_Dilution: User Optimized
Flow_Cytometry_Dilution: 5 uL/test/1x10e5 to 1x10e8 cells
Western_Blot_Dilution: User Optimized
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说明
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Anti-CD80 is tested for Flow Cytometry and useful in Immunohistochemistry and Western Blot. Researchers should determine optimal titers for applications that are not stated.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.2 % BSA (w/v)
Preservative: 0.09 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.
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有效期
- 6 months
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- CD80
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别名
- CD80
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背景
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Synonyms: T-lymphocyte activation antigen CD80, Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B7.1, B7, CD80, CD28LG, CD28LG1, LAB7
Background: CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.
Gene Name: CD80
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基因ID
- 941
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NCBI登录号
- NP_005182
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UniProt
- P33681
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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