Androgen Receptor 抗体 (pSer94)
Our Local Distributor
北京 101111
Quick Overview for Androgen Receptor 抗体 (pSer94) (ABIN6655077)
抗原
See all Androgen Receptor (AR) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer94
-
Supplier Product No.
- 600-401-w93
-
Supplier
- Rockland
-
原理
- Androgen Receptor phospho S94 Antibody
-
交叉反应 （详细）
- This antibody is specific for phosphorylated Androgen Receptor.
-
纯化方法
- Anti-Phospho-Ser94 Androgen Receptor Antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities.
-
过滤
- Sterile filtered
-
免疫原
- Anti-Phospho-Ser94 Androgen Receptor Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding the phosphorylated Ser94 of human AR conjugated to KLH.
-
亚型
- IgG
-
-
anti-Androgen Receptor (AR) (N-Term) antibody
AR 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) antibodyAR 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Androgen Receptor (AR) (Center) antibodyAR 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 491-679) antibodyAR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Androgen Receptor (AR) (N-Term) antibodyVerified AR 适用: 人 WB, IHC, ELISA, IF, ChIP 宿主: 山羊 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 221-320) antibodyAR 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1G3 unconjugated
anti-Androgen Receptor (AR) (AA 15-246) antibodyAR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 365-392) antibodyAR 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (AA 825-919) antibodyAR 适用: 人, 小鼠, 大鼠, Pig, 山羊 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Androgen Receptor (AR) (pSer578) antibodyAR 适用: 人, 小鼠, 大鼠 IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA_Dilution: 1:10,000
Western_Blot_Dilution: 1:1000
-
说明
-
Anti-Phospho-Ser94 Androgen Receptor Antibody is tested for Western blots. Expect a band at approximately ~110 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
Preservative: None -
储存液
- Without preservative
-
储存条件
- -20 °C
-
储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
- Androgen Receptor (AR)
-
别名
- Androgen Receptor
-
背景
-
Synonyms: Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Background: The androgen receptor (AR) is a DNA-binding transcription factor that regulates genes critical for the development and maintenance of the male sexual phenotype. Defects in androgen receptor have been shown to play a role in prostate cancer, and inhibition of AR activity through modulation of signal transduction pathways may delay prostate cancer progression. Multiple phosphorylation sites have been identified on the androgen receptor that affect cross-talk between growth factor signaling and androgen in prostate development and cancer. One of these sites, at Ser94, appears constitutively phosphorylated and exhibits no response to treatments with stimulating hormone. The site at Ser94 is unique among the AR phosphorylation sites in that it does not achieve a maximal level of phosphorylation between translation and the initial round of nuclear import, having a strong bias for androgen-independent phosphorylation in the cytoplasm. Androgen Receptor pS94 Antibody is ideal for researchers interested in cancer research.
Gene Name: AR
-
基因ID
- 367
-
NCBI登录号
- NP_001011645
-
UniProt
- P10275
-
途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
-
