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Elastase 3B 抗体 (AA 82-238)

This anti-Elastase 3B antibody is a 兔 单克隆 antibody detecting Elastase 3B in IHC (p). Suitable for 人.
产品编号 ABIN6655004
发货至: 中国

Quick Overview for Elastase 3B 抗体 (AA 82-238) (ABIN6655004)

抗原

See all Elastase 3B (ELA3B) 抗体
Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

适用

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宿主

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克隆类型

  • 103
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单克隆

标记

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This Elastase 3B antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

CELA3B-2809R
  • 抗原表位

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    AA 82-238

    纯化方法

    Purified

    纯度

    Protein A affinity chromatography

    免疫原

    A recombinant partial protein (aa 82-238) was used as the immunogen for the recombinant CELA3B antibody.

    亚型

    IgG kappa
  • 应用备注

    Optimal dilution of the recombinant CELA3B antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

    限制

    仅限研究用
  • 缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant CELA3B antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

    别名

    CELA3B / Elastase 3B

    背景

    This MAb recognizes a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B). Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function.
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