Recombinant DC-SIGN/CD209 抗体
Our Local Distributor
北京 101111
Quick Overview for Recombinant DC-SIGN/CD209 抗体 (ABIN6654643)
抗原
See all DC-SIGN/CD209 (CD209) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
-
-
原理
- DC-SIGN Antibody / CD209 (azide and preservative free)
-
纯化方法
- Protein A affinity chromatography
-
免疫原
- Recombinant human protein was used as the immunogen for the DC-SIGN antibody.
-
亚型
- IgG, kappa
-
-
-
-
应用备注
-
Optimal dilution of the DC-SIGN antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the DC-SIGN antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- DC-SIGN/CD209 (CD209) (CD209)
-
别名
- DC-SIGN
-
背景
- DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
-
UniProt
- Q9NNX6
抗原
-