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Recombinant DC-SIGN/CD209 抗体

The 兔 单克隆 anti-DC-SIGN/CD209 antibody is suitable to detect DC-SIGN/CD209 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN6654643
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant DC-SIGN/CD209 抗体 (ABIN6654643)

抗原

See all DC-SIGN/CD209 (CD209) 抗体
DC-SIGN/CD209 (CD209) (CD209)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This DC-SIGN/CD209 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

C209-2749R
  • 原理

    DC-SIGN Antibody / CD209 (azide and preservative free)

    纯化方法

    Protein A affinity chromatography

    免疫原

    Recombinant human protein was used as the immunogen for the DC-SIGN antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the DC-SIGN antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the DC-SIGN antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    DC-SIGN/CD209 (CD209) (CD209)

    别名

    DC-SIGN

    背景

    DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

    UniProt

    Q9NNX6
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