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DC-SIGN/CD209 抗体

This anti-DC-SIGN/CD209 antibody is a 兔 单克隆 antibody detecting DC-SIGN/CD209 in IHC (p). Suitable for 人.
产品编号 ABIN6654643
发货至: 中国

Quick Overview for DC-SIGN/CD209 抗体 (ABIN6654643)

抗原

See all DC-SIGN/CD209 (CD209) 抗体
DC-SIGN/CD209 (CD209) (CD209)

适用

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宿主

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克隆类型

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单克隆

标记

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This DC-SIGN/CD209 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

C209-2749R
  • 纯化方法

    Purified

    纯度

    Protein A affinity chromatography

    免疫原

    Recombinant human protein was used as the immunogen for the DC-SIGN antibody.

    亚型

    IgG kappa
  • 应用备注

    Optimal dilution of the DC-SIGN antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL,Prediluted IHC only format: incubate for 30 min at RT (1)

    限制

    仅限研究用
  • 缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the DC-SIGN antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原

    DC-SIGN/CD209 (CD209) (CD209)

    别名

    DC-SIGN / CD209

    背景

    DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
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