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Recombinant Desmin 抗体

The 兔 单克隆 anti-Desmin antibody (Clone DES-2960R) (ABIN6654512) specifically detects Desmin in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN6654512
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant Desmin 抗体 (ABIN6654512)

抗原

See all Desmin (DES) 抗体
Desmin (DES)

抗体类型

Recombinant Antibody

适用

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单克隆

标记

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This Desmin antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

DES-2960R
  • 原理

    Recombinant Desmin Antibody (azide and preservative free)

    纯化方法

    Protein A affinity chromatography

    免疫原

    Recombinant human protein was used as the immunogen for the recombinant Desmin antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the recombinant Desmin antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the recombinant Desmin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Desmin (DES)

    别名

    Desmin

    背景

    Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.

    UniProt

    P17661
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